Mi Sarah J, Kelly Nichole R, Brychta Robert J, Grammer Anne Claire, Jaramillo Manuela, Chen Kong Y, Fletcher Laura A, Bernstein Shanna B, Courville Amber B, Shank Lisa M, Pomeroy Jeremy J, Brady Sheila M, Broadney Miranda M, Tanofsky-Kraff Marian, Yanovski Jack A
Section on Growth and Obesity, Program in Endocrinology, Metabolism and Genetics, Division of Intramural Research Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Department of Health and Human Services (DHHS), Bethesda, MD, USA.
Departments of Counseling Psychology and Human Services, and Prevention Science, University of Oregon, Eugene, OR, USA.
Pediatr Obes. 2019 Jun;14(6):e12507. doi: 10.1111/ijpo.12507. Epub 2019 Jan 31.
Self-reported short sleep duration is associated with greater risk for metabolic syndrome (MetS), obesity, and higher energy intake (EI). However, studies of these associations in children using objective methods are sparse.
The study aims to determine the associations for sleep patterns with MetS indices, body composition, and EI using objective measures in children.
Free-living sleep and physical activity were measured in 125 children (aged 8-17 years, BMI z = 0.57 ± 1.0, 55% female) using wrist-worn actigraphs for 14 nights. Blood pressure, fasting blood levels of lipids, insulin, glucose, waist circumference, and body composition (dual-energy X-ray absorptiometry [DXA]) were obtained during outpatient visits. EI was assessed during an ad libitum buffet meal.
Later weekday and weekend bedtimes were associated with higher systolic blood pressure (Ps < 0.05). Sleep duration and bedtime were not significantly associated with other components of MetS, body composition, or EI. Short sleepers (duration less than 7 hours) consumed a greater percentage of carbohydrates than those with adequate (greater than or equal to 7 hours) sleep (P < 0.05).
Indicators of sleep duration were variably associated with children's eating patterns and risk for chronic disease. Prospective data are needed to determine whether these indicators of sleep quality represent unique or shared risk factors for poor health outcomes.
自我报告的短睡眠时间与代谢综合征（MetS）、肥胖及更高的能量摄入（EI）风险增加相关。然而，使用客观方法对儿童进行的这些关联研究较少。
本研究旨在通过客观测量确定儿童睡眠模式与MetS指标、身体成分及EI之间的关联。
使用腕部活动记录仪对125名儿童（年龄8 - 17岁，BMI z值 = 0.57 ± 1.0，55%为女性）进行为期14晚的自由生活睡眠和身体活动测量。在门诊就诊时获取血压、空腹血脂、胰岛素、血糖、腰围及身体成分（双能X线吸收法[DXA]）数据。在随意自助餐期间评估EI。
工作日和周末较晚的就寝时间与较高的收缩压相关（P < 0.05）。睡眠时间和就寝时间与MetS的其他成分、身体成分或EI无显著关联。睡眠不足者（睡眠时间少于7小时）碳水化合物摄入量占比高于睡眠充足者（大于或等于7小时）（P < 0.05）。
睡眠时间指标与儿童饮食模式及慢性病风险存在不同程度的关联。需要前瞻性数据来确定这些睡眠质量指标是否代表健康不良结局的独特或共同风险因素。
