Centro Ocular, Heredia, Costa Rica; Instituto de Oftalmología Fundación Conde de Valenciana, Ciudad de México, México.
Instituto de Oftalmología Fundación Conde de Valenciana, Ciudad de México, México.
Surv Ophthalmol. 2019 Jul-Aug;64(4):463-476. doi: 10.1016/j.survophthal.2019.01.009. Epub 2019 Jan 28.
Toxic anterior segment syndrome is a surgical complication characterized by a noninfectious anterior chamber inflammatory reaction having multiple etiologies. The clinical signs (prominent limbus-to-limbus corneal edema, anterior chamber inflammation) and symptoms (decreased visual acuity, discomfort) generally occur within the first 12-48 hours after intraocular surgery. Most patients achieve good clinical and visual outcomes when there is a prompt clinical diagnosis and adequate treatment. We review the literature on toxic anterior segment syndrome, emphasizing its etiology, pathophysiology, and clinical and surgical management, as well as prognosis and sequelae. Our goal is to reduce the frequency of toxic anterior segment syndrome by highlighting the importance of prevention, early recognition, and distinguishing toxic anterior segment syndrome from infectious endophthalmitis.
毒性前节综合征是一种以非感染性前房炎症反应为特征的手术并发症，具有多种病因。临床体征（明显的角膜缘到角膜缘水肿，前房炎症）和症状（视力下降，不适）通常在眼内手术后的 12-48 小时内出现。大多数患者在及时进行临床诊断和充分治疗后，可获得良好的临床和视觉效果。我们回顾了毒性前节综合征的文献，强调了其病因、病理生理学以及临床和手术处理，还有预后和后遗症。我们的目标是通过强调预防、早期识别以及将毒性前节综合征与感染性眼内炎区分开来的重要性，来降低毒性前节综合征的发生率。
