Barkhane Zineb, Qureshi Maria, Jamil Ahmed, Chowdhury Purnashree, Kamran Muhammad, Altayb Ismail Mohamedalamin Alnoor, Saeed Shahzeb
Faculté de Médecine et de Pharmacie, Université Hassan II de Casablanca, Casablanca, MAR.
Family Medicine, Ayub Medical College, Abbottabad, PAK.
Cureus. 2023 Jun 18;15(6):e40584. doi: 10.7759/cureus.40584. eCollection 2023 Jun.
Diabetes can lead to various acute clinical complications, although the occurrence of ophthalmic signs and symptoms is uncommon. Neovascular glaucoma (NG), a rare complication associated with diabetes mellitus, is one such condition. Additionally, anti-vascular endothelial growth factor (VEGF)-induced toxic anterior segment syndrome (TASS) is a rare complication of intravitreal bevacizumab. In this case report, we present a unique case of a patient with juvenile diabetes (type 1 diabetes mellitus) who presented to the emergency room (ER) with typical features of diabetic ketoacidosis (DKA) accompanied by bilateral ocular pain. Subsequent investigation revealed secondary angle-closure neovascular glaucoma as the underlying cause. The patient received management for DKA in the ER and subsequent medicine ward. Various interventions were performed for glaucoma in the right eye, including addressing cataracts, which ultimately resulted in TASS. The patient was successfully treated with cryo-diode laser therapy.
糖尿病可导致各种急性临床并发症，尽管眼部体征和症状并不常见。新生血管性青光眼（NG）是一种与糖尿病相关的罕见并发症，就是这样一种情况。此外，抗血管内皮生长因子（VEGF）诱导的毒性眼前节综合征（TASS）是玻璃体内注射贝伐单抗的罕见并发症。在本病例报告中，我们介绍了一名患有青少年糖尿病（1型糖尿病）的患者的独特病例，该患者因糖尿病酮症酸中毒（DKA）的典型特征并伴有双侧眼痛而到急诊室就诊。随后的检查发现继发性闭角型新生血管性青光眼是根本原因。患者在急诊室和随后的内科病房接受了DKA的治疗。对右眼青光眼进行了各种干预，包括处理白内障，最终导致了TASS。患者通过冷冻二极管激光治疗成功治愈。
