再生障碍性贫血的诊断与治疗

[Diagnosis and treatment of aplastic anemia].

作者信息

Kleihauer E

机构信息

Abteilung Kinderheilkunde II, Universitäts-Kinderklinik und Poliklinik Ulm.

出版信息

Monatsschr Kinderheilkd. 1988 Dec;136(12):772-8.

Abstract

Severe aplastic anemia is a rare disorder in childhood. Among various therapeutical strategies bone marrow transplantation (BMT) and immunosuppressive treatment with antithymocyte globulin (ATG) have proven to be most successful. Priority should be given to BMT over ATG treatment for patients with HLA-identical donors. Patients with Fanconi's anemia require a reduced conditioning program with cyclophosphamide and irradiation for BMT. Own experiences indicate that cooperative studies are highly needed to improve medical care for patients with severe aplastic anemia.

摘要

重型再生障碍性贫血是儿童期的一种罕见疾病。在各种治疗策略中，骨髓移植（BMT）和抗胸腺细胞球蛋白（ATG）免疫抑制治疗已被证明是最成功的。对于有 HLA 匹配供者的患者，BMT 应优先于 ATG 治疗。范可尼贫血患者进行 BMT 时需要减少环磷酰胺和放疗的预处理方案。我们自己的经验表明，迫切需要开展合作研究以改善重型再生障碍性贫血患者的医疗护理。

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1

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[Bone marrow transplantation and (or) immunosuppression with antithymocyte globulin in the treatment of aplastic anemia].[骨髓移植和（或）用抗胸腺细胞球蛋白进行免疫抑制治疗再生障碍性贫血]

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