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[加蓬的脊椎结核。解剖临床方面、诊断和治疗问题,1976年至1986年的107例病例]

[Vertebral tuberculosis in Gabon. Anatomo-clinical aspects, diagnostic and therapeutic problems, 107 cases from 1976 to 1986].

作者信息

Loembe P M, Assengone-Zeh Y, Guerch M, Mbumb-King A

机构信息

Service de Neurochirurgie, Fondation Jeanne-Ebori, Libreville, Gabon, Afrique Equatoriale.

出版信息

Neurochirurgie. 1988;34(6):420-7.

PMID:3070425
Abstract

This retrospective study covers a period of 10.5 years (february 1976 to november 1986). It concerns 107 patients who contracted tuberculous spondylitis and originated from different provinces of Gabon. The authors report their experiences in order to emphasize the frequency of the disease, diagnostic and therapeutic problems. In Gabon, tuberculosis of the spine occupies the third position (3%), after the pulmonary form (90%) and ganglionic form (3.8%). In also represents 83.6% of the osteoarticular tuberculosis. The average age is 22 years, 55% of the patients were less than 20 years. The zone of maximum predilection, in decreasing order, is thoracic spine (36.4%), lumbar spine (33.6%), thoraco-lumbar region (10.3%). The 107 patients totalized 257 vertebral bodies destroyed (an average of 2.4 bodies per patients). On the clinical field the sick seek advice at an advance stage of the disease with gibbosity (38.3%) and neurologic deficits (21.5%). The diagnosis proof often followed the therapeutic results. There were three therapeutic modalities: medical (all patients), surgical (6 patients) and orthopedic (44 patients). The therapeutic indications improved with the available of more material and qualified staff. In children the treatment remains classic. The authors discuss the surgical indications in adults. The therapeutic results in patients treated and followed for over one year were satisfactory. Unfortunately, most patients were lost to follow-up. They suggest public health means of decreasing the frequency of the disease.

摘要

这项回顾性研究涵盖了10.5年的时间段(1976年2月至1986年11月)。研究涉及107例患有结核性脊柱炎的患者,他们来自加蓬的不同省份。作者报告了他们的经验,以强调该疾病的发病率、诊断和治疗问题。在加蓬,脊柱结核占第三位(3%),仅次于肺结核(90%)和淋巴结结核(3.8%)。它也占骨关节结核的83.6%。平均年龄为22岁,55%的患者年龄小于20岁。最易受累的部位依次为胸椎(36.4%)、腰椎(33.6%)、胸腰段(10.3%)。107例患者共有257个椎体被破坏(平均每位患者2.4个椎体)。在临床方面,患者在疾病晚期出现脊柱后凸(38.3%)和神经功能缺损(21.5%)时才就医。诊断证据往往依据治疗结果。有三种治疗方式:药物治疗(所有患者)、手术治疗(6例患者)和矫形治疗(44例患者)。随着更多材料和专业人员的到位,治疗指征得到了改善。儿童的治疗仍为传统方式。作者讨论了成人的手术指征。接受治疗并随访一年以上的患者治疗结果令人满意。不幸的是,大多数患者失访。他们提出了降低该疾病发病率的公共卫生措施。

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Tuberculosis of the lower cervical spine (C3-C7) in adults: diagnostic and surgical aspects.
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