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宫颈癌及其前驱病变:筛查、诊断与管理的预防性方法

Cervical Cancer and Its Precursors: A Preventative Approach to Screening, Diagnosis, and Management.

作者信息

Stumbar Sarah E, Stevens Maria, Feld Zoe

机构信息

Department of Humanities, Health, and Society, Herbert Wertheim College of Medicine, Florida International University, 11200 Southwest 8th Street, Miami, FL 33199, USA.

Department of Humanities, Health, and Society, Herbert Wertheim College of Medicine, Florida International University, 11200 Southwest 8th Street, Miami, FL 33199, USA.

出版信息

Prim Care. 2019 Mar;46(1):117-134. doi: 10.1016/j.pop.2018.10.011. Epub 2018 Dec 22.

Abstract

Cervical cancer affects the cells lining the cervix, most commonly occurring in the cells of the transformation zone. Screening for cervical cancer looks to detect preinvasive disease, allowing for intervention before invasive disease develops. an assessment of individual risk factors, Selection of screening method depends on patient age, her screening history and results, and resources available. Screening has resulted in well-documented declines in cervical cancer incidence and mortality in the United States. Guidelines continue to evolve as new data emerge. Although cervical cancer prevention strategies include interventions directed toward limiting number of sexual partners, condom use, and reduction in cigarette smoking, vaccination represents the most direct targeted strategy.

摘要

宫颈癌影响子宫颈内膜细胞,最常见于转化区细胞。宫颈癌筛查旨在检测癌前病变,以便在浸润性疾病发生之前进行干预。筛查方法的选择取决于个体风险因素、患者年龄、其筛查史和结果以及可用资源。在美国,筛查已使宫颈癌的发病率和死亡率显著下降,且有充分记录。随着新数据的出现,指南也在不断演变。虽然宫颈癌预防策略包括限制性伴侣数量、使用避孕套和减少吸烟等干预措施,但接种疫苗是最直接的针对性策略。

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