Kim Donggyu, Englund Dirk R
Department of Mechanical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
Research Laboratory of Electronics, Massachusetts Institute of Technology, 50 Vassar Street, Cambridge, MA 02139, USA.
Science. 2019 Feb 1;363(6426):528-531. doi: 10.1126/science.aar8609.
Optical scattering is generally considered to be a nuisance of microscopy that limits imaging depth and spatial resolution. Wavefront shaping techniques enable optical imaging at unprecedented depth, but attaining superresolution within complex media remains a challenge. We used a quantum reference beacon (QRB), consisting of solid-state quantum emitters with spin-dependent fluorescence, to provide subwavelength guidestar feedback for wavefront shaping to achieve a superresolution optical focus. We implemented the QRB-guided imaging with nitrogen-vacancy centers in diamond nanocrystals, which enable optical focusing with a subdiffraction resolution below 186 nanometers (less than half the wavelength). QRB-assisted wavefront-shaping should find use in a range of applications, including deep-tissue quantum enhanced sensing and individual optical excitation of magnetically coupled spin ensembles for applications in quantum information processing.
光散射通常被认为是显微镜成像中的一个麻烦，它限制了成像深度和空间分辨率。波前整形技术能够实现前所未有的深度光学成像，但在复杂介质中实现超分辨率仍然是一个挑战。我们使用了一种量子参考信标（QRB），它由具有自旋相关荧光的固态量子发射器组成，为波前整形提供亚波长引导星反馈，以实现超分辨率光学聚焦。我们利用金刚石纳米晶体中的氮空位中心实现了QRB引导成像，该中心能够实现低于186纳米（小于波长的一半）的亚衍射分辨率的光学聚焦。QRB辅助的波前整形应能在一系列应用中得到应用，包括深部组织量子增强传感以及用于量子信息处理的磁耦合自旋系综的单个光学激发。
