Nanjing Municipal Center for Disease Control and Prevention, Nanjing, 210003, Jiangsu Province, China.
School of Public Health of Southeast University, Nanjing, 210009, Jiangsu Province, China.
Environ Monit Assess. 2019 Jan 31;191(2):119. doi: 10.1007/s10661-019-7239-0.
This study developed a new method to determine the residues of 13 organophosphorus flame retardants (OPFRs) in drinking water by gas chromatography-tandem mass spectrometry (GC-MS/MS) technique and investigated the chemical distribution in water samples from municipal plants along the Yangtze River in Nanjing. The linear calibration correlation coefficients R for all 13 OPFRs were at least 0.998 0. Three levels of spiked test were performed. Most of the recoveries were in the range of 80120%, and the relative standard deviations (RSDs) for the 13 OPFRs were 2.117% (n = 6). Five OPFRs were 100% positively detected in the samples, and 3 OPFRs were positively detected in some samples. The concentrations of detected OPFR in the water ranged from 0.7 to 5780.0 ng L. The average concentrations of OPFRs in wet season were higher than those in dry season, and the contaminants mainly originated from the source water in the Yangtze River. The exposure assessments of individual and total OPFRs were investigated. The estimated daily intakes of total OPFRs via ingestion of drinking water reached up to 64.8 and 45.2 ng/kg bw/day in dry and wet season, respectively. This study demonstrates a profile of OPFR distribution in Nanjing municipal water and provides information on human exposure assessment via drinking water in the Nanjing District, China.
本研究建立了一种新的方法，通过气相色谱-串联质谱（GC-MS/MS）技术测定饮用水中 13 种有机磷阻燃剂（OPFRs）的残留量，并研究了南京市沿长江市政水厂水样中的化学分布。所有 13 种 OPFR 的线性校准相关系数 R 均至少为 0.9980。进行了三个水平的加标测试。大多数回收率在 80%120%之间，13 种 OPFR 的相对标准偏差（RSD）为 2.1%17%（n=6）。在样品中 100%检测到 5 种 OPFR，在某些样品中检测到 3 种 OPFR。检测到的水中 OPFR 浓度范围为 0.7 至 5780.0 ng/L。雨季 OPFR 浓度的平均值高于旱季，污染物主要来自长江原水。对个体和总 OPFR 的暴露评估进行了研究。通过饮用水摄入的总 OPFR 的估计日摄入量在旱季和雨季分别高达 64.8 和 45.2 ng/kg bw/day。本研究展示了南京市市政水中 OPFR 分布情况，并提供了中国南京市通过饮用水进行人体暴露评估的信息。
