Department of GEMS, Health Studies Institute, Rider University, Lawrenceville, New Jersey.
Am J Ind Med. 2019 Apr;62(4):337-346. doi: 10.1002/ajim.22955. Epub 2019 Jan 31.
Temporal trends and broad geographical distributions of asbestos use and the incidence of malignant mesothelioma (MM) in the US still need to be studied.
Data on asbestos consumption and production between 1900 and 2015 and MM mortality and incidence rates between 1975 and 2015 in the US were examined. Spatial distributions of MM mortality and incidence rates and their association with climate zone were analyzed.
Decline of MM incidence and mortality rates in the US occurred about 20 years after the peak of asbestos consumption-production in 1973. There are apparent north-south (N-S) gradients in MM mortality and incidence rates in the US.
Recent decline of MM incidence and mortality rates in the US may be associated with reduced US asbestos consumption. N-S MM gradients between 1999 and 2015 were likely related to larger asbestos requirements in building materials in the northern states.
仍需研究美国石棉使用的时间趋势和广泛的地域分布，以及恶性间皮瘤（MM）的发病率。
本研究调查了 1900 年至 2015 年美国石棉消费和生产数据，以及 1975 年至 2015 年美国 MM 死亡率和发病率数据。分析了 MM 死亡率和发病率的空间分布及其与气候带的关系。
美国 MM 的发病率和死亡率在 1973 年石棉消费和生产达到峰值后约 20 年开始下降。美国 MM 的死亡率和发病率存在明显的南北（N-S）梯度。
美国 MM 的发病率和死亡率近期的下降可能与美国石棉消费的减少有关。1999 年至 2015 年南北 MM 梯度可能与北部各州建筑材料中更大的石棉需求有关。
