Nicholson W J, Raffn E
Department of Community Medicine, Mount Sinai Medical Center, New York, NY, U
Med Lav. 1995 Sep-Oct;86(5):393-410.
The Authors present data, from the USA and Denmark, dealing with the carcinogenicity of chrysotile. This review considers epidemiological studies on the incidence of bronchogenic carcinoma and mesothelioma in populations exposed to commercial chrysotile and to mixtures of chrysotile and commercial amphiboles, with which the chrysotile is often contaminated. The analyses demonstrate that the risk of lung cancer is similar for chrysotile, amosite and crocidolite on a fiber exposure basis. Chrysotile and amosite appear to produce equal mesothelioma risks. The risk of mesothelioma is four to ten times greater for crocidolite.
作者展示了来自美国和丹麦的有关温石棉致癌性的数据。本综述考虑了关于商业温石棉以及温石棉与商业角闪石混合物(温石棉常被其污染)暴露人群中支气管源性癌和间皮瘤发病率的流行病学研究。分析表明,基于纤维暴露量,温石棉、铁石棉和青石棉导致肺癌的风险相似。温石棉和铁石棉似乎产生相同的间皮瘤风险。青石棉导致间皮瘤的风险要高4至10倍。