Vergracht A, Valentin N, Bignon J D, Patereau C, Muller J Y
Laboratoire d'Immunologie leuco-plaquettaire, CRTS, Nantes.
Rev Fr Transfus Immunohematol. 1988 Dec;31(5):697-709. doi: 10.1016/s0338-4535(88)80078-3.
In this study, we describe a flow cytometric technic for the detection and characterization of platelet allo antibodies and for platelets grouping in the platelet group PLA. This new technique is a variant of the platelet suspension immuno fluorescence test. It is rapid, simple, sensitive and specific. So it is very useful in the cases of neonatal thrombocytopenia and posttransfusion purpura. Moreover, anti-HLA antibodies don't obstruct the detection of anti-PLA1 antibodies.
在本研究中，我们描述了一种流式细胞术技术，用于检测和鉴定血小板同种抗体以及对血小板组PLA中的血小板进行分组。这项新技术是血小板悬液免疫荧光试验的一种变体。它快速、简单、灵敏且特异。因此，它在新生儿血小板减少症和输血后紫癜病例中非常有用。此外，抗HLA抗体不会妨碍抗PLA1抗体的检测。
