谷氨酸受体功能的代谢组学分析
Metabolomics Analysis of Glutamate Receptor Function.
作者信息
Chorna Nataliya E, Chornyy Anatoliy P
机构信息
Department of Biochemistry, School of Medicine, University of Puerto Rico, San Juan, PR, USA.
PR-INBRE Metabolomics Research Core, School of Medicine, University of Puerto Rico, San Juan, PR, USA.
出版信息
Methods Mol Biol. 2019;1941:155-165. doi: 10.1007/978-1-4939-9077-1_11.
Abstract
Metabolomics analysis provides a unique opportunity for comprehensive mapping of glutamatergic system function using high-throughput metabolite analysis and providing a perspective of the enzymatic activity, which cannot be obtained by other systems biology techniques.
摘要
代谢组学分析为利用高通量代谢物分析全面描绘谷氨酸能系统功能并提供酶活性的视角提供了独特机会，而这是其他系统生物学技术无法实现的。
相似文献
1
Metabolomics Analysis of Glutamate Receptor Function.谷氨酸受体功能的代谢组学分析
Methods Mol Biol. 2019;1941:155-165. doi: 10.1007/978-1-4939-9077-1_11.
3
Metabolomic Strategies Involving Mass Spectrometry Combined with Liquid and Gas Chromatography.涉及质谱联用液相色谱和气相色谱的代谢组学策略。
Adv Exp Med Biol. 2017;965:77-98. doi: 10.1007/978-3-319-47656-8_4.
4
Glutamate enrichment as new diagnostic opportunity in breast cancer.谷氨酸富集作为乳腺癌新的诊断契机。
Int J Cancer. 2015 Apr 1;136(7):1619-28. doi: 10.1002/ijc.29152. Epub 2014 Sep 4.
5
Metabolic profiling of tyrosine, tryptophan, and glutamate in human urine using gas chromatography-tandem mass spectrometry combined with single SPE cleanup.采用气相色谱-串联质谱联用结合单次固相萃取净化法对人尿液中的酪氨酸、色氨酸和谷氨酸进行代谢谱分析。
J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Apr 15;1051:97-107. doi: 10.1016/j.jchromb.2017.03.015. Epub 2017 Mar 16.
6
Metabolic Characterization of Myocardial Infarction Using GC-MS-Based Tissue Metabolomics.基于气相色谱-质谱联用技术的组织代谢组学对心肌梗死的代谢特征分析
Int Heart J. 2017 May 31;58(3):441-446. doi: 10.1536/ihj.16-432. Epub 2017 May 8.
7
Untargeted Soil Metabolomics Using Liquid Chromatography-Mass Spectrometry and Gas Chromatography-Mass Spectrometry.使用液相色谱-质谱联用和气相色谱-质谱联用的非靶向土壤代谢组学
Methods Mol Biol. 2019;1859:97-109. doi: 10.1007/978-1-4939-8757-3_4.
8
Mass Spectrometry-Based Metabolomics.基于质谱的代谢组学
Methods Mol Biol. 2018;1775:107-118. doi: 10.1007/978-1-4939-7804-5_10.
9
Highly sensitive and selective analysis of widely targeted metabolomics using gas chromatography/triple-quadrupole mass spectrometry.采用气相色谱/三重四极杆质谱法进行高灵敏度和高选择性的广泛靶向代谢组学分析。
J Biosci Bioeng. 2014 Jan;117(1):122-8. doi: 10.1016/j.jbiosc.2013.06.009. Epub 2013 Jul 16.
10
Analysis of Metabolite Profiling in Human Endothelial Cells after Plasma Jet Treatment.等离子体射流处理后人内皮细胞代谢产物分析。
Biomed Res Int. 2019 Nov 3;2019:3015150. doi: 10.1155/2019/3015150. eCollection 2019.
引用本文的文献
1
Exploring the interplay between running exercises, microbial diversity, and tryptophan metabolism along the microbiota-gut-brain axis.探索跑步运动、微生物多样性和色氨酸代谢在微生物群-肠-脑轴上的相互作用。
Front Microbiol. 2024 Jan 22;15:1326584. doi: 10.3389/fmicb.2024.1326584. eCollection 2024.
2
A Protocol for the Multi-Omic Integration of Cervical Microbiota and Urine Metabolomics to Understand Human Papillomavirus (HPV)-Driven Dysbiosis.一项用于整合宫颈微生物群和尿液代谢组学以了解人乳头瘤病毒（HPV）驱动的生态失调的多组学方案。
Biomedicines. 2020 Apr 8;8(4):81. doi: 10.3390/biomedicines8040081.
本文引用的文献
1
Metabolomic Analysis in Brain Research: Opportunities and Challenges.脑研究中的代谢组学分析：机遇与挑战。
Front Physiol. 2016 May 24;7:183. doi: 10.3389/fphys.2016.00183. eCollection 2016.
2
MetaboAnalyst 3.0--making metabolomics more meaningful.MetaboAnalyst 3.0——让代谢组学更具意义。
Nucleic Acids Res. 2015 Jul 1;43(W1):W251-7. doi: 10.1093/nar/gkv380. Epub 2015 Apr 20.
3
Standardizing GC-MS metabolomics.标准化气相色谱-质谱联用代谢组学
J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Aug 15;871(2):191-201. doi: 10.1016/j.jchromb.2008.04.049. Epub 2008 May 21.
4
A metabolomic approach to ionotropic glutamate receptor subtype function: a nuclear magnetic resonance in vitro investigation.一种针对离子型谷氨酸受体亚型功能的代谢组学方法：体外核磁共振研究
J Cereb Blood Flow Metab. 2006 Aug;26(8):1005-17. doi: 10.1038/sj.jcbfm.9600257. Epub 2005 Dec 14.
5
Effects of L-glutamate transport inhibition by a conformationally restricted glutamate analogue (2S,1'S,2'R)-2-(carboxycyclopropyl)glycine (L-CCG III) on metabolism in brain tissue in vitro analysed by NMR spectroscopy.通过核磁共振光谱分析构象受限的谷氨酸类似物（2S，1'S，2'R）-2-（羧基环丙基）甘氨酸（L-CCG III）抑制L-谷氨酸转运对体外脑组织代谢的影响。
Neurochem Res. 2002 Feb;27(1-2):27-35. doi: 10.1023/a:1014842303583.
Zotero 插件