Turhan Sadullah
Antalya Training and Research Hospital, Department of Orthopaedics and Traumatology, Antalya, Turkey.
Surg Infect (Larchmt). 2019 Apr;20(3):244-246. doi: 10.1089/sur.2018.123. Epub 2019 Feb 1.
Total knee arthroplasty (TKA) is performed to improve the quality of life by reducing knee arthralgia. One of the most destructive and expensive complications of TKA is deep infection. The primary purpose of this study was to evaluate the effect of using antibiotic-loaded bone cement (ALBC) on the incidence of deep infection after primary TKA.
A total of 506 patients who underwent primary knee arthroplasty at the Antalya Training and Research Hospital between February 2009 and January 2016 were investigated retrospectively.
The ALBC was used for 85 patients (16.7%), who constituted group 1. Plain bone cement was used for 421 patients (83.2%), who constituted group 2. Deep infection was observed in one patient (1.1%) in group 1 and in six patients (1.4%) in group 2, a difference that is not statistically significant. On average, the deep infection occurred six months after the surgery at the earliest and 19 months at the latest.
Use of ALBC did not decrease the incidence of deep infection in TKA. Therefore, we prefer bone cement without any antibiotic.
全膝关节置换术（TKA）旨在通过减轻膝关节疼痛来提高生活质量。TKA最具破坏性且成本高昂的并发症之一是深部感染。本研究的主要目的是评估使用含抗生素骨水泥（ALBC）对初次TKA后深部感染发生率的影响。
对2009年2月至2016年1月在安塔利亚培训与研究医院接受初次膝关节置换术的506例患者进行回顾性研究。
85例患者（16.7%）使用了ALBC，构成第1组。421例患者（83.2%）使用了普通骨水泥，构成第2组。第1组有1例患者（1.1%）发生深部感染，第2组有6例患者（1.4%）发生深部感染，差异无统计学意义。深部感染最早在术后6个月出现，最晚在19个月出现。
使用ALBC并未降低TKA中深部感染的发生率。因此，我们更倾向于使用不含任何抗生素的骨水泥。
