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[继发性免疫缺陷在痢疾发病机制中的重要性]

[The importance of secondary immune deficiencies in the pathogenesis of dysentery].

作者信息

Mashilov V P, Usychenko E M

出版信息

Ter Arkh. 1988;60(11):63-4.

PMID:3070808
Abstract

Some immunity indices were studied in patients with acute dysentery. The number of total and active T-lymphocytes, T mu- and T gamma-cells, T-rabbit, T-staphylococcal, B-total and B-lymphocytes forming rosettes with mouse erythrocytes were determined for assessment of the immune status. Changes in the above indices with relation to the severity of the disease were noted. Suppression of the T- and B-systems of immunity were noticeable in patients with a severe and lingering course of disease. Delayed time of complete convalescence was observed in patients with a marked imbalance of indices of the T- and B-systems of immunity during convalescence.

摘要

对急性痢疾患者的一些免疫指标进行了研究。测定了总T淋巴细胞和活性T淋巴细胞、Tμ细胞和Tγ细胞、T兔细胞、T葡萄球菌细胞、总B淋巴细胞以及与小鼠红细胞形成玫瑰花结的B淋巴细胞数量,以评估免疫状态。记录了上述指标随疾病严重程度的变化。在病情严重且迁延不愈的患者中,T和B免疫系统受到明显抑制。在康复期T和B免疫系统指标明显失衡的患者中,观察到完全康复的时间延迟。

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