Department of Neurology, Division of Respirology, Neurology and Rheumatology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan.
Department of Neurology, Division of Respirology, Neurology and Rheumatology, Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan.
Mult Scler Relat Disord. 2019 Apr;29:108-110. doi: 10.1016/j.msard.2019.01.035. Epub 2019 Jan 23.
There are no specific radiologic features in MOG-Ab (autoantibodies directed against myelin oligodendrocyte glycoprotein)-associated diseases. We present two MOG-Ab-positive patients with symmetrical lesions in the bilateral cingulate cortex of the frontal and parietal lobes. Those lesions showed hyperperfusion in acute phase and hypoperfusion in chronic phase on brain SPECT. In both patients, steroid therapy was effective in acute phase and for prevention of recurrence. High signal in the bilateral cingulate cortex on MR T2-weighted and FLAIR images might to be one of the unique findings considered MOG-Ab associated diseases.
MOG-Ab（针对少突胶质细胞髓鞘糖蛋白的自身抗体）相关疾病并无特定的放射影像学特征。我们报告了 2 例 MOG-Ab 阳性患者，其双侧额顶叶扣带回皮质存在对称性病变。这些病变在脑 SPECT 上急性期呈高灌注，慢性期呈低灌注。在这 2 例患者中，急性期和预防复发应用类固醇治疗均有效。MR T2 加权和 FLAIR 图像上双侧扣带回皮质的高信号可能是被认为与 MOG-Ab 相关疾病相关的独特表现之一。
