Elkins A D, Jones L P
School of Veterinary Medicine, Louisiana State University, Baton Rouge 70803.
Vet Surg. 1988 Mar-Apr;17(2):71-6. doi: 10.1111/j.1532-950x.1988.tb00280.x.
Four one quarter inch evenly spaced circular defects were created bilaterally in the lateral femoral diaphysis of 12 clinically normal adult dogs. The defects were left unfilled (control), or were filled with one of the following: (1) plaster of Paris, (2) an equal-volume mixture of plaster of Paris and autogenous cancellous bone, and (3) autogenous cancellous bone. The degree of bone healing was evaluated radiographically and histologically at 2, 4, 6, 8, 10, and 12 weeks. Radiographically, no objective conclusions could be drawn due to the small size of the defects and limited amount of plaster of Paris implanted. Histologically, there was no inflammatory reaction to the plaster of Paris. No differences were determined in the degree of bone healing between autogenous cancellous bone, plaster of Paris, and a mixture of plaster of Paris and autogenous cancellous bone. All implants were superior to the control defect in degree of bone healing.
在12只临床健康的成年犬的股骨干外侧，双侧制造4个四分之一英寸、间距均匀的圆形缺损。缺损处不进行填充（对照组），或填充以下材料之一：（1）巴黎石膏，（2）等量的巴黎石膏与自体松质骨的混合物，（3）自体松质骨。在2、4、6、8、10和12周时，通过影像学和组织学评估骨愈合程度。在影像学上，由于缺损尺寸小且植入的巴黎石膏量有限，无法得出客观结论。在组织学上，对巴黎石膏没有炎症反应。自体松质骨、巴黎石膏以及巴黎石膏与自体松质骨的混合物之间，在骨愈合程度上未发现差异。所有植入物在骨愈合程度上均优于对照缺损。
