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用于测试血管移植物的破裂强度装置的设计与分析

Design and analysis of a burst strength device for testing vascular grafts.

作者信息

Pérez-Aranda C, Gamboa F, Castillo-Cruz O, Cauich-Rodríguez J V, Avilés F

机构信息

Centro de Investigación Científica de Yucatán, A.C., Unidad de Materiales, Calle 43 #130 x 32 y 34, Col. Chuburná de Hidalgo, C.P. 97205 Mérida, Yucatán, Mexico.

Centro de Investigación y de Estudios Avanzados, Unidad Mérida, Departamento de Física Aplicada, A.P. 73 Cordemex, 97310 Mérida, Yucatán, Mexico.

出版信息

Rev Sci Instrum. 2019 Jan;90(1):014301. doi: 10.1063/1.5037578.

DOI:10.1063/1.5037578
PMID:30709208
Abstract

The design and analysis of a device to measure the burst strength (strength under a state of pure radial internal pressure) and compliance of vascular grafts and flexible pressurized tubes is presented. The device comprises three main sections, viz., a clean air-dry pressure controller, a test specimen holder, and automated software for control and data collection. Air pressure is controlled by means of a valve and a dedicated mechanism allowing reaching up to 120 psi in increments of 1 psi, and recording pressure changes with 0.04 psi resolution. The circumferential strain is determined by measuring the radial displacement of the vascular graft using an optical arrangement capable of determining a maximum radial displacement of 10 mm with 0.02 mm resolution. The instrument provides a low uncertainty in compliance (±0.32%/100 mm Hg) and burst strength measurements. Due to its simplicity, the device can easily be reproduced in other laboratories contributing to a dedicated instrument with high resolution at low cost. The reliability of the apparatus is further confirmed by conducting finite element analysis, elasticity solutions for pressurized cylinders, and testing of small diameter vascular grafts made of a commercial aliphatic polyurethane tested under radial internal pressure.

摘要

本文介绍了一种用于测量血管移植物和柔性压力管的爆破强度(纯径向内压状态下的强度)及顺应性的装置的设计与分析。该装置包括三个主要部分,即清洁空气 - 干燥压力控制器、试样支架以及用于控制和数据采集的自动化软件。气压通过一个阀门和一个专用机构进行控制,能够以1 psi的增量达到120 psi,并以0.04 psi的分辨率记录压力变化。周向应变通过使用一种光学装置测量血管移植物的径向位移来确定,该光学装置能够以0.02 mm的分辨率确定最大10 mm的径向位移。该仪器在顺应性(±0.32%/100 mmHg)和爆破强度测量方面具有低不确定性。由于其简单性,该装置可以很容易地在其他实验室复制,从而以低成本打造出一台具有高分辨率的专用仪器。通过进行有限元分析、压力圆柱体的弹性解以及对在径向内压下测试的商用脂肪族聚氨酯制成的小直径血管移植物进行测试,进一步证实了该仪器的可靠性。

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