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成年患者儿童期有髋关节感染病史,全髋关节置换术后的临床结果和生活质量:一项中期随访研究。

Clinical outcomes and quality of life after total hip arthroplasty in adult patients with a history of infection of the hip in childhood: a mid-term follow-up study.

作者信息

Luo Yue, Yang Zhouyuan, Yeersheng Releken, Li Donghai, Kang Pengde

机构信息

Department of Orthopedics, West China Hospital, Sichuan University, 37# Wainan Guoxue Road, Chengdu, 610041, Sichuan, People's Republic of China.

出版信息

J Orthop Surg Res. 2019 Feb 1;14(1):38. doi: 10.1186/s13018-019-1074-4.

Abstract

BACKGROUND

Total hip arthroplasty for adult patients with a history of infection of the hip in childhood could be a more technically demanding procedure due to complicated anatomy and the possibility of reinfection. Here, we conducted a mid-term analysis of clinical outcomes in such patients after primary cementless total hip arthroplasty (THA).

METHODS

We reviewed 101 patients (101 hips; 51 men; mean age, 52.3 years) who underwent cementless THA between 2008 and 2015, at a mean of 24 years (range, 11-43) since the resolution of childhood hip infection. Patients were followed up for a mean of 6.1 years (range, 2.1-9.6). Clinical outcomes and quality of life after THA were assessed at final follow-up.

RESULTS

No cases of infection were reported during the follow-up, and patients showed significant improvement in Harris Hip Score, for which the mean score increased from 48.5 to 90 points; the modified Merle d'Aubigne and Postel (MAP) Hip Score; the Hip Dysfunction and Osteoarthritis Outcome Score; the SF-12; and mean limb length discrepancy, which decreased from 3.4 to 1.1 cm. During follow-up, four cases of prosthesis dislocation, three of transient sciatic paralysis, seven of femoral fracture, five of heterotopic ossification, and 19 of osteolysis were recorded. Revision surgery was performed for two patients, one for isolated loosening of the acetabular component and another for loosening of the femoral stem.

CONCLUSION

Cementless THA can effectively treat patients with a quiescent period of infection of the hip of more than 10 years, resulting in good functional outcomes and fewer complications. Risk of infection recurrence after THA in these patients seems extremely low.

摘要

背景

对于童年时有髋关节感染病史的成年患者,全髋关节置换术可能因解剖结构复杂及再次感染的可能性而在技术上要求更高。在此,我们对这类患者初次非骨水泥型全髋关节置换术(THA)后的临床结果进行了中期分析。

方法

我们回顾了2008年至2015年间接受非骨水泥型THA的101例患者(101髋;51例男性;平均年龄52.3岁),自童年髋关节感染痊愈后平均24年(范围11 - 43年)。患者平均随访6.1年(范围2.1 - 9.6年)。在末次随访时评估THA后的临床结果和生活质量。

结果

随访期间未报告感染病例,患者的Harris髋关节评分有显著改善,平均评分从48.5分提高到90分;改良Merle d'Aubigne和Postel(MAP)髋关节评分;髋关节功能障碍和骨关节炎结果评分;SF - 12;平均肢体长度差异从3.4厘米降至1.1厘米。随访期间,记录到4例假体脱位、3例短暂性坐骨神经麻痹、7例股骨骨折、5例异位骨化和19例骨溶解。2例患者进行了翻修手术,1例因髋臼部件孤立性松动,另1例因股骨柄松动。

结论

非骨水泥型THA可有效治疗髋关节感染静止期超过10年的患者,功能结果良好且并发症较少。这些患者THA后感染复发的风险似乎极低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aa9/6359810/a74ece7d2a5d/13018_2019_1074_Fig1_HTML.jpg

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