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简化的风险预测指标不能准确预测结直肠手术后 30 天的死亡或再入院率。

Simplified risk prediction indices do not accurately predict 30-day death or readmission after discharge following colorectal surgery.

机构信息

Department of Surgery, Washington University School of Medicine, St. Louis, MO.

Department of Medicine, Washington University School of Medicine.

出版信息

Surgery. 2019 May;165(5):882-888. doi: 10.1016/j.surg.2018.12.007. Epub 2019 Jan 29.

Abstract

BACKGROUND

Risk-prediction indices are one category of the many tools implemented to guide efforts to decrease readmissions. However, using fied models to predict a complex process can prove challenging. In addition, no risk-prediction index has been developed for patients undergoing colorectal surgery. Therefore, we evaluated the performance of a widely utilized simplified index developed at the hospital level - LACE (length of stay, acute admission, Charlson comorbidity index score, and emergency department visits) and developed and evaluated a novel index in predicting readmissions in this patient population.

METHODS

Using a retrospective split-sample cohort, patients discharged after colorectal surgery were identified within the inpatient databases of the Healthcare Cost and Utilization Project for the states of New York, California, and Florida (2006-2014). The primary outcome was death or readmission within 30 days after discharge. Multivariable logistic regression models incorporated patient comorbidities, postoperative complications, and hospitalization details, and were evaluated using the C statistic.

RESULTS

A total of 440,742 patients met eligibility criteria. The rate of death or readmission within 30 days after discharge was 14.0% (n = 61,757). When applied to surgical patients, the LACE index demonstrated a poor model fit (C = 0.631). The model fit improved significantly-but remained poor (C = 0.654; P < .001)-with the addition of the following variables, which are known to be associated with readmission after colorectal surgery: age, indication for surgery, and creation of a new ostomy. A novel, simplified model also yielded a poor model fit (C = 0.660).

CONCLUSION

Postdischarge death or readmission after colorectal surgery is not accurately modeled using existing, modified, or novel simplified risk prediction models. Payers and providers must ensure that quality improvement efforts applying simplified models to complex processes, such as readmissions following colorectal surgery, may not be appropriate, and that models reflect the relevant patient population.

摘要

背景

风险预测指标是用于指导降低再入院率的众多工具之一。然而,使用固定模型来预测复杂的过程可能具有挑战性。此外,尚未为接受结直肠手术的患者开发风险预测指标。因此,我们评估了一种广泛使用的简化医院级别模型- LACE(住院时间、急性入院、Charlson 合并症指数评分和急诊就诊)的性能,并开发并评估了一种预测该患者人群再入院的新指标。

方法

使用回顾性拆分样本队列,从纽约州、加利福尼亚州和佛罗里达州的医疗保健成本和利用项目的住院患者数据库中确定接受结直肠手术后出院的患者(2006-2014 年)。主要结局是出院后 30 天内死亡或再入院。多变量逻辑回归模型纳入了患者合并症、术后并发症和住院详细信息,并使用 C 统计量进行评估。

结果

共有 440,742 名患者符合入选标准。出院后 30 天内死亡或再入院的发生率为 14.0%(n=61,757)。当应用于手术患者时,LACE 指数的模型拟合效果不佳(C=0.631)。添加已知与结直肠手术后再入院相关的以下变量后,模型拟合显著改善-但仍然较差(C=0.654;P<.001):年龄、手术指征和新造口术。一个新的简化模型也产生了较差的模型拟合(C=0.660)。

结论

使用现有的、修改后的或新的简化风险预测模型无法准确预测结直肠手术后出院后的死亡或再入院。付款人和提供者必须确保将简化模型应用于复杂过程(例如结直肠手术后的再入院)的质量改进工作可能不合适,并且模型反映了相关的患者人群。

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