Adegun Oluyori Kutulola, Morley Simon, Kalavrezos Nicholas, Jay Amrita
Head and Neck Pathology Unit, Histopathology, University College London Hospitals, NHS Foundation Trust, London, UK.
Radiology (Imaging), University College London Hospitals, NHS Foundation Trust, London, UK.
BMJ Case Rep. 2019 Feb 1;12(2):e226567. doi: 10.1136/bcr-2018-226567.
A 70-year-old woman presented with a 10-month history of an irregular mass in the left lateral nape of her neck which had recently increased in size rapidly. Ultrasound-guided core needle biopsy was obtained, and the tumour was diagnosed as a well-differentiated squamous cell carcinoma. Further imaging studies failed to demonstrate additional malignant characteristics. In view of these findings, a wide local excision of the tumour was performed. Histopathological assessment of the resected tumour revealed a proliferating trichilemmal tumour with well-differentiated features and smooth invasion front. This article serves as an important reminder of the challenges associated with pathological evaluation of core needle biopsies of adnexal tumours. It emphasises the importance of clinical-radiological-pathological correlation preferably in a multidisciplinary team setting prior to agreeing on a definitive management plan.
一名70岁女性，左侧颈后出现不规则肿块10个月，近期肿块迅速增大。在超声引导下进行了粗针穿刺活检，肿瘤被诊断为高分化鳞状细胞癌。进一步的影像学检查未发现其他恶性特征。鉴于这些发现，对肿瘤进行了广泛的局部切除。对切除肿瘤的组织病理学评估显示为增生性外毛根鞘瘤，具有高分化特征且浸润前沿光滑。本文重要地提醒了在附件肿瘤粗针穿刺活检的病理评估中存在的挑战。它强调了在确定最终治疗方案之前，最好在多学科团队环境中进行临床-放射-病理相关性分析的重要性。
