Drozd Brandy, Andriescu Elena, Suárez Andrea, De la Garza Bravo Maria Migeulina
McGovern Medical School of University of Texas Houston Health Science Center, Houston, Texas.
Dermatol Online J. 2019 Jan 15;25(1):13030/qt84f936cp.
The possible presentations of cytomegalovirus (CMV) are vast not only in its systemic manifestations, but also in the various cutaneous lesions that may result. Cutaneous cytomegalovirus is rarely reported in the literature because the clinical and pathologic features can be difficult to identify. Its identification, however, is vital as cutaneous human CMV infection can signal systemic disease and an unfavorable prognosis. The objective of this study is to aid in recognition, diagnosis, and treatment of CMV according to dermatological evidence. A complete literature search was performed within PubMed, resulting in the inclusion of 58 patient cases. The most common dermatologic manifestation was perianal or oral ulcers, but the locations and types of lesions noted throughout the review were numerous. Treatment is often simple, yet incorrect diagnoses along with concurrent illnesses can often complicate management. It is imperative for CMV to be detected early in its course to prevent mortality, especially in the immunocompromised. Dermatological presentations are often the first sign of this deadly virus' activity and it is essential that these diagnoses are made more efficient and accurate.
巨细胞病毒（CMV）的可能表现形式繁多，不仅体现在其全身症状上，还体现在可能导致的各种皮肤病变中。皮肤巨细胞病毒在文献中鲜有报道，因为其临床和病理特征可能难以识别。然而，其识别至关重要，因为皮肤人类巨细胞病毒感染可能预示着全身性疾病和不良预后。本研究的目的是根据皮肤病学证据协助巨细胞病毒的识别、诊断和治疗。在PubMed上进行了全面的文献检索，纳入了58例患者病例。最常见的皮肤表现是肛周或口腔溃疡，但在整个综述中记录的病变部位和类型众多。治疗通常简单，但错误的诊断以及并发疾病常常使管理复杂化。必须在病程早期检测到巨细胞病毒以预防死亡，尤其是在免疫功能低下的患者中。皮肤表现往往是这种致命病毒活动的首个迹象，提高这些诊断的效率和准确性至关重要。
