Bellomo L E, Rosset N, Tellarini L, Forconesi N
Facultad de Medicina UBA, Buenos Aires, Argentina.
Acta Psiquiatr Psicol Am Lat. 1988 Sep;34(3):230-6.
Bromperidol therapeutic efficacy, and tolerance was studied by means of a 3-month open trial on 25 chronic psychotic female inpatients from a room at San Juan ward for medium to extensive length of stay, The Braulio A. Moyano National Psychiatric Hospital, Buenos Aires. This drug was administered orally on a single 10- to 35 mg night dose. No effect whatsoever was observed on periodic catatonia. However, its being well-tolerated and effective on chronic psychotic patients, coupled to the "bonus" of a single daily dose, turns BP into a suitable alternative drug for Haloperidol when dealing with schizophrenia, and delusions with no deficitary evolution.
通过对布宜诺斯艾利斯市布劳利奥·A·莫亚诺国家精神病院圣胡安病房25名长期住院的慢性精神病女性患者进行为期3个月的开放试验,研究了溴哌利多的治疗效果和耐受性。该药物采用每晚10至35毫克的单一口服剂量给药。对周期性紧张症未观察到任何效果。然而,它对慢性精神病患者耐受性良好且有效,再加上每日单次给药的“优势”,使得在治疗精神分裂症和无衰退性妄想时,溴哌利多成为氟哌啶醇的合适替代药物。