Bataille M
Acta Psychiatr Belg. 1978 Jan-Feb;78(1):173-9.
Bromperidol was administered to 20 acute and chronic psychotic inpatients during six to eight weeks at a mean daily dose of 18 to 10 mg. The neuroleptic was given orally or intramuscularly once a day (in the morning in order to evaluate its therapeutic and side effects). In 13 patients, bromperidol was substituted for haloperidol; in 7 cases, it was given immediately after the washout period. Descriptive psychopathology was complemented with quantitative psychopathology (ad hoc 29-item scale, AMDP Psychopathology Scale, Bf/Bf' Mood Scales). According to a preliminary analysis of data, both descriptive and psychometric, bromperidol seems to be a potent antipsychotic drug without disturbing adrenolytic side-effects or sedation, with classical extrapyramidal effects of the hypertonia type.
对20名急性和慢性精神病住院患者给予溴哌利多，疗程为6至8周，平均日剂量为18至10毫克。该抗精神病药物每天口服或肌肉注射一次（早晨给药，以便评估其治疗效果和副作用）。13名患者中，用溴哌利多替代了氟哌啶醇；7例在洗脱期后立即给予溴哌利多。描述性精神病理学辅以定量精神病理学（特制的29项量表、AMDP精神病理量表、Bf/Bf'情绪量表）。根据对数据的初步分析，无论是描述性还是心理测量方面，溴哌利多似乎都是一种有效的抗精神病药物，不会产生干扰肾上腺素的副作用或镇静作用，具有张力亢进型的典型锥体外系反应。
