Division of Infectious Diseases, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
J Infect Public Health. 2019 May-Jun;12(3):309-312. doi: 10.1016/j.jiph.2019.01.059. Epub 2019 Jan 30.
Septic arthritis is a common rheumatologic condition with myriad microbiological causative agents. Moraxella is one of the very rare causes of septic arthritis. We hereby present the third case of Moraxella nonliquefaciens septic arthritis and the first case in a hematopoietic stem cell transplant patient (HSCT) along with a brief review of the literature.
We used PubMed with google search engine to search the literature for reported cases of moraxella septic arthritis.
Information on 19 other cases of moraxella infectious arthritis was found. M. catarrhalis was the most common species isolated. Only 2 reports on M. nonliquefaciens were found; the first one in a multiple myeloma patient and the second one in a diabetic patient on hemodialysis. Predisposing conditions included inflammatory arthritis, prosthetic joints, diabetes, Human Immunodeficiency Virus (HIV) infection, Hepatitis C, hemodialysis, esophageal cancer, valve replacements, alcoholism and Intravenous (IV) drug use. The age group of the reported cases ranged from 3 months to 78 years.
Infectious arthritis with Moraxella spp. is a very rare entity which can occur in any age group and in the setting of various underlying medical conditions.
化脓性关节炎是一种常见的风湿性疾病,有多种微生物病原体。莫拉菌属是引起化脓性关节炎的罕见病因之一。我们在此报告第三例莫拉菌非液化亚种化脓性关节炎,也是首例造血干细胞移植(HSCT)患者的病例,并对文献进行了简要回顾。
我们使用 PubMed 和谷歌搜索引擎查阅了文献中报道的莫拉菌化脓性关节炎病例。
共发现 19 例其他莫拉菌感染性关节炎病例。分离出的最常见菌种为卡他莫拉菌。仅发现 2 例莫拉菌非液化亚种的报告;第一例发生在多发性骨髓瘤患者中,第二例发生在糖尿病血液透析患者中。易患因素包括炎症性关节炎、人工关节、糖尿病、人类免疫缺陷病毒(HIV)感染、丙型肝炎、血液透析、食管癌、瓣膜置换、酒精中毒和静脉(IV)药物使用。报告病例的年龄从 3 个月到 78 岁不等。
莫拉菌属引起的化脓性关节炎非常罕见,可发生于任何年龄组,也可发生于多种基础疾病。