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立体定向方法对儿童和青少年深部脑局灶性病变的诊断价值。

Diagnostic value of the stereotactic approach to focal lesions in the deep brain of children and adolescents.

作者信息

Schmitt H P, Wowra B, Sturm V

机构信息

Institute of Neuropathology, University of Heidelberg Medical School, Germany (FRG).

出版信息

Brain Dev. 1988;10(5):305-11. doi: 10.1016/s0387-7604(88)80061-5.

DOI:10.1016/s0387-7604(88)80061-5
PMID:3071166
Abstract

Since it is relatively harmless, stereotactic biopsy has become in recent years a useful method for the diagnostic assessment of lesions deep in the brain, which are not accessible to open surgery. With the aid of stereotaxis, focal lesions only a few millimeters in diameter can be approached in every location in the brain with high precision. Since stereotaxis does not require general anesthesia, or at most requires only a very shallow anesthesia, it can also be applied to young infants or persons of advanced age. Experience with stereotactic biopsy exploration of lesions of various kinds in the deep brain of 74 children and adolescents, out of a sample of 260 patients of all age groups who received stereotactic biopsy, is reported. Our aim is to demonstrate and discuss the advantage of this contemporary method for child neurology and neurosurgery. In many medical centers in the world where stereotactic tumor biopsy has been established, it has become an important criterion for the choice of treatment.

摘要

由于立体定向活检相对无害,近年来它已成为一种用于诊断评估脑深部病变的有用方法,这些病变无法通过开放手术触及。借助立体定向技术,直径仅几毫米的局灶性病变在脑内的任何位置都能以高精度进行操作。由于立体定向不需要全身麻醉,或者最多只需要非常浅的麻醉,它也可应用于幼儿或高龄患者。本文报告了在接受立体定向活检的所有年龄组的260例患者样本中,对74例儿童和青少年脑深部各种病变进行立体定向活检探索的经验。我们的目的是展示和讨论这种现代方法对儿童神经学和神经外科的优势。在世界上许多已开展立体定向肿瘤活检的医疗中心,它已成为治疗选择的重要标准。

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Diagnostic value of the stereotactic approach to focal lesions in the deep brain of children and adolescents.立体定向方法对儿童和青少年深部脑局灶性病变的诊断价值。
Brain Dev. 1988;10(5):305-11. doi: 10.1016/s0387-7604(88)80061-5.
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引用本文的文献

1
Technique of stereotactic biopsy in a 5-month-old child.
Childs Nerv Syst. 1996 Oct;12(10):615-8. doi: 10.1007/BF00261657.
2
Stereotactic techniques in managing pediatric brain tumors.小儿脑肿瘤治疗中的立体定向技术
Childs Nerv Syst. 1993 Sep;9(6):343-6; discussion 347. doi: 10.1007/BF00302038.
3
Incidence of late radiation necrosis with transient mass effect after interstitial low dose rate radiotherapy for cerebral gliomas.
Acta Neurochir (Wien). 1989;99(3-4):104-8. doi: 10.1007/BF01402316.