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进行性假性类风湿发育不良:三例报告及影像学和磁共振成像表现回顾。

Progressive pseudorheumatoid dysplasia: a report of three cases and a review of radiographic and magnetic resonance imaging findings.

机构信息

Department of Radiology, New York-Presbyterian Hospital/Weill Cornell Medicine, 525 E. 68th St., F631E, New York, NY, 10065, USA.

Department of Radiology, The Children's Hospital of Philadelphia, 34th Street & Civic Center Boulevard, Philadelphia, PA, 19104, USA.

出版信息

Skeletal Radiol. 2019 Sep;48(9):1323-1328. doi: 10.1007/s00256-019-3165-z. Epub 2019 Feb 2.

Abstract

Progressive pseudorheumatoid dysplasia (PPD) is a rare disorder of postnatal skeletal and cartilage development that often presents with similar clinical findings to juvenile idiopathic arthritis. Patients with PPD display findings of progressive cartilage loss and secondary osteoarthritis over serial imaging studies and have an absence of elevation of inflammatory markers. Awareness of the imaging features of PPD on radiographs and magnetic resonance imaging (MRI) may be important for early diagnosis and surveillance of the disease.

摘要

进行性假类风湿发育不良(PPD)是一种罕见的产后骨骼和软骨发育疾病,其临床表现常与幼年特发性关节炎相似。PPD 患者在系列影像学研究中表现出进行性软骨丧失和继发性骨关节炎的表现,且炎症标志物水平无升高。在 X 线摄影和磁共振成像(MRI)上了解 PPD 的影像学特征对于早期诊断和疾病监测可能很重要。

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