• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

人类绝经的演变。

The evolution of the human menopause.

机构信息

a Department of Reproductive and Maternal Medicine , University of Glasgow , Glasgow , UK.

b Department of Obstetrics and Gynaecology , Princess Royal Maternity Hospital , Glasgow , UK.

出版信息

Climacteric. 2019 Apr;22(2):111-116. doi: 10.1080/13697137.2018.1547701. Epub 2019 Feb 4.

DOI:10.1080/13697137.2018.1547701
PMID:30712396
Abstract

The females of most species die soon after ceasing to reproduce, their purpose in life being to ensure survival of their kin. Human females may live more than one-third of their lives after they cease to reproduce, a property shared by few species, one of which is Orca whales. Orcas have been extensively studied because families live together in stable units or pods and individual whales have distinctive markings, enabling them to be identified. The females survive long after the menopause, one possible reason for this being that the older females provide a survival advantage since they are seen to lead the pods more often than younger females or males, thus providing a survival advantage in times of food shortage. The female lifespan is increasing in most countries worldwide, principally due to decreased infection and maternal mortality. Women are now more active through middle and into older age. Whatever sort of life they wish to lead, women need to be as fit as possible to facilitate healthy aging. Chronic diseases that affect millions of women are cardiovascular disease, osteoporosis, cancer, and dementia. The incidence of all these is increased by obesity, the prevention of which is a major challenge in our society. Hormone therapy may have a place for some women but for many others taking control of their health by lifestyle intervention is a major contributor to disease prevention. It is our duty as doctors to encourage this at every opportunity to help all women live a fruitful and healthy old age.

摘要

大多数物种的雌性在停止繁殖后不久就会死亡,它们生命的目的是确保其亲属的生存。人类女性在停止生育后可能会活过生命的三分之一,这是少数几种物种所共有的特性,其中之一就是逆戟鲸。逆戟鲸被广泛研究,因为它们的家庭以稳定的单位或群体生活在一起,而且每只鲸鱼都有独特的标记,可以识别它们。雌性在绝经后还能存活很长时间,一个可能的原因是,年长的雌性提供了生存优势,因为它们比年轻的雌性或雄性更经常领导群体,从而在食物短缺时提供了生存优势。在世界上大多数国家,女性的寿命都在延长,这主要是由于感染和产妇死亡率的降低。女性现在在中年和老年时期更加活跃。无论她们希望过什么样的生活,女性都需要尽可能保持健康,以促进健康衰老。影响数百万女性的慢性疾病包括心血管疾病、骨质疏松症、癌症和痴呆症。所有这些疾病的发病率都因肥胖而增加,预防肥胖是我们社会面临的主要挑战。激素疗法可能对某些女性适用,但对许多其他女性来说,通过生活方式干预来控制自己的健康是预防疾病的主要因素。作为医生,我们有责任在任何机会都鼓励这种做法,以帮助所有女性过上富有成效和健康的晚年生活。

相似文献

1
The evolution of the human menopause.人类绝经的演变。
Climacteric. 2019 Apr;22(2):111-116. doi: 10.1080/13697137.2018.1547701. Epub 2019 Feb 4.
2
Ecological knowledge, leadership, and the evolution of menopause in killer whales.生态知识、领导力与虎鲸更年期的演化
Curr Biol. 2015 Mar 16;25(6):746-750. doi: 10.1016/j.cub.2015.01.037. Epub 2015 Mar 5.
3
Reproductive Conflict and the Evolution of Menopause in Killer Whales.生殖冲突与虎鲸的绝经期进化。
Curr Biol. 2017 Jan 23;27(2):298-304. doi: 10.1016/j.cub.2016.12.015. Epub 2017 Jan 12.
4
Life history evolution: what does a menopausal killer whale do?生活史进化:绝经后的虎鲸做什么?
Curr Biol. 2015 Mar 16;25(6):R225-R227. doi: 10.1016/j.cub.2015.02.002.
5
Prevention of diseases after menopause.绝经后疾病的预防。
Climacteric. 2014 Oct;17(5):540-56. doi: 10.3109/13697137.2014.933411. Epub 2014 Jun 27.
6
The evolution of menopause in toothed whales.有齿鲸类动物绝经期的进化。
Nature. 2024 Mar;627(8004):579-585. doi: 10.1038/s41586-024-07159-9. Epub 2024 Mar 13.
7
Postreproductive female killer whales reduce socially inflicted injuries in their male offspring.繁殖后的雌性虎鲸会减少其雄性后代身上的社交性伤害。
Curr Biol. 2023 Aug 7;33(15):3250-3256.e4. doi: 10.1016/j.cub.2023.06.039. Epub 2023 Jul 20.
8
Menopause: Hormones, Lifestyle, and Optimizing Aging.更年期:激素、生活方式与优化衰老。
Obstet Gynecol Clin North Am. 2019 Sep;46(3):501-514. doi: 10.1016/j.ogc.2019.04.008. Epub 2019 Jun 21.
9
Temporal dynamics of mother-offspring relationships in Bigg's killer whales: opportunities for kin-directed help by post-reproductive females.大村氏海豚母婴关系的时间动态:生殖后雌性提供亲缘导向帮助的机会。
Proc Biol Sci. 2023 Jun 14;290(2000):20230139. doi: 10.1098/rspb.2023.0139. Epub 2023 Jun 7.
10
Epidemiology and the menopause: a global overview.流行病学与更年期:全球概述
Int J Fertil Menopausal Stud. 1993;38 Suppl 1:6-14.

引用本文的文献

1
Sex differences in musculoskeletal injury and disease risks across the lifespan: Are there unique subsets of females at higher risk than males for these conditions at distinct stages of the life cycle?一生中肌肉骨骼损伤和疾病风险的性别差异:在生命周期的不同阶段,是否存在比男性患这些疾病风险更高的特定女性亚群体?
Front Physiol. 2023 Apr 11;14:1127689. doi: 10.3389/fphys.2023.1127689. eCollection 2023.
2
Genotype Is Associated with Increased Total Cholesterol and Low-Density Lipoprotein Levels in Menopausal Women with a Body Mass Index of at Least 25 kg/m.基因型与体重指数至少为25kg/m²的绝经后女性总胆固醇和低密度脂蛋白水平升高有关。
Pathophysiology. 2020 Dec 30;28(1):1-9. doi: 10.3390/pathophysiology28010001.
3
Describing the status of reproductive ageing simply and precisely: A reproductive ageing score based on three questions and validated with hormone levels.
简洁而准确地描述生殖衰老的状况:基于三个问题的生殖衰老评分,并通过激素水平验证。
PLoS One. 2020 Jun 30;15(6):e0235478. doi: 10.1371/journal.pone.0235478. eCollection 2020.
4
The relationship between management strategies for menopausal symptoms and women's decision making styles during menopausal transition.绝经过渡期间更年期症状管理策略与女性决策风格之间的关系。
Prz Menopauzalny. 2019 Dec;18(3):174-179. doi: 10.5114/pm.2019.90378. Epub 2019 Dec 4.
5
Cardiovascular Disease and the Female Disadvantage.心血管疾病与女性劣势。
Int J Environ Res Public Health. 2019 Apr 1;16(7):1165. doi: 10.3390/ijerph16071165.