酮体对骨骼肌的抗分解代谢作用。
Anticatabolic Effects of Ketone Bodies in Skeletal Muscle.
机构信息
Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
National Institute for Cellular Biotechnology, School of Health and Human Performance, Dublin City University, Glasnevin, Dublin 9, Ireland.
出版信息
Trends Endocrinol Metab. 2019 Apr;30(4):227-229. doi: 10.1016/j.tem.2019.01.006. Epub 2019 Jan 31.
The ketone bodies acetoacetate (AcAc) and β-hydroxybutyrate (βHB) are the subject of renewed interest given recently established pleiotropic effects regulating inflammation, oxidative stress, and gene expression. Anticatabolic effects of β-hydroxybutyrate have recently been demonstrated in human skeletal muscle under inflammatory insult, thereby expanding upon the wide-ranging therapeutic applications of nutritional ketosis.
酮体乙酰乙酸（AcAc）和 β-羟丁酸（βHB）是近年来备受关注的物质，它们具有调节炎症、氧化应激和基因表达的多效性作用。最近在人类骨骼肌中炎症损伤的情况下，已经证明了 β-羟丁酸的抗分解代谢作用，从而扩展了营养性酮症的广泛治疗应用。
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