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[冰岛的莱姆病——2011年至2015年的流行病学情况]

[Lyme disease in Iceland - Epidemiology from 2011 to 2015].

作者信息

Vigfusson Hannes Bjarki, Hardarson Hordur Snaevar, Ludviksson Bjorn Runar, Gudlaugsson Olafur

机构信息

Department of clinical microbiology, Landspítali University Hospital.

Department of clinical microbiology, Landspítali University Hospital, Department of paediatrics, Landspítali University Hospital.

出版信息

Laeknabladid. 2019 Feb;105(2):63-70. doi: 10.17992/lbl.2019.02.215.

Abstract

INTRODUCTION

Lyme disease is caused by an infection with Borrelia burgdorferi sensu latu (B. burgdorferi sl.) which is carried by Ixodes ticks. The disease has not been considered to be endemic in Iceland and no cases of Icelandic origin have been published. The epidemiology of Lyme disease in Iceland has never been studied. The objective of this study was to provide basic epidemiological information about Lyme disease in Iceland.

MATERIAL AND METHODS

Included in the study were all pa--tients who had a measurement of serum antibodies against B. burgdorferi sl. or were diagnosed with Lyme disease (ICD-10, A69.2) at Landspítali University Hospital in Iceland from 2011-2015. Clinical data regarding these patients was retrospectively collected from medical records and the database of the Department of clinical microbiology at Landspítali University Hospital.

RESULTS

501 patient had a measurement of serum antibodies against B. burgdorferi sl. and 11 patients were clinically diag-nosed with Lyme disease during the study period. 33 patients fulfilled criteria for a confirmed diagnosis of Lyme disease. 32 (97%) patients had erythema migrans and one (3%) patient had neuroborreliosis. An average of 6.6 cases were diagnosed a year (two cases per 100,000 persons/year). All cases originated abroad.

CONCLUSIONS

Lyme disease is rare in Iceland. On average around 6 to 7 cases are diagnosed every year, primarily localised infec-tions presenting as erythema migrans. None of the cases had a definitive Icelandic origin and the yearly number of cases has not been increasing.

摘要

引言

莱姆病由伯氏疏螺旋体复合群(Borrelia burgdorferi sensu latu,B. burgdorferi sl.)感染引起,该病原体由硬蜱携带。莱姆病在冰岛未被视为地方性疾病,也没有发表过源自冰岛的病例。冰岛莱姆病的流行病学从未被研究过。本研究的目的是提供冰岛莱姆病的基本流行病学信息。

材料与方法

纳入研究的是2011年至2015年期间在冰岛Landspítali大学医院进行过抗B. burgdorferi sl.血清抗体检测或被诊断为莱姆病(国际疾病分类第十版,A69.2)的所有患者。这些患者的临床数据是从Landspítali大学医院的病历和临床微生物学系数据库中回顾性收集的。

结果

在研究期间,501名患者进行了抗B. burgdorferi sl.血清抗体检测,11名患者被临床诊断为莱姆病。33名患者符合莱姆病确诊标准。32名(97%)患者出现游走性红斑,1名(3%)患者患有神经型伯氏疏螺旋体病。平均每年诊断出6.6例病例(每10万人/年2例)。所有病例均源自国外。

结论

莱姆病在冰岛很罕见。平均每年诊断出约6至7例病例,主要表现为以游走性红斑为主的局部感染。没有一例病例有明确的冰岛起源,且每年的病例数没有增加。

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