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临床罕见的溶血隐秘杆菌菌血症并发足部压疮溃疡:给基层医疗医生的警示

Clinically Infrequent Arcanobacterium haemolyticum Bacteremia Complicated by Foot Decubitus Ulcer: An Educational Reminder for Primary Care Physicians.

作者信息

Takamura Noriko, Tada Katsushige, Ishioka Haruhiko, Gomi Harumi

机构信息

Center for Global Health, Mito Kyodo General Hospital, University of Tsukuba, Japan.

出版信息

Intern Med. 2019 Jun 1;58(11):1645-1647. doi: 10.2169/internalmedicine.2162-18. Epub 2019 Feb 1.

DOI:10.2169/internalmedicine.2162-18
PMID:30713320
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6599926/
Abstract

An 81-year-old Japanese man with no history of diabetes mellitus was admitted to our hospital for a fever with a new ulcerative lesion on the left heel. Blood cultures on admission grew Arcanobacterium haemolyticum in aerobic bottles. He was therefore diagnosed with A. haemolyticum bacteremia and osteomyelitis complicated with foot decubitus ulcer. He was successfully treated with intravenous antibiotic therapy and debridement of the left heel. Our case and literature review show that it is important to recognize that A. haemolyticum is a systemic causative pathogen in immunocompetent patients in primary care practice.

摘要

一名81岁无糖尿病病史的日本男性因发热伴左脚跟部新发溃疡性病变入住我院。入院时血培养在需氧瓶中培养出溶血隐秘杆菌。因此,他被诊断为溶血隐秘杆菌菌血症和骨髓炎并发足部褥疮溃疡。通过静脉抗生素治疗和左脚跟清创术,他得到了成功治疗。我们的病例及文献回顾表明,在初级医疗实践中,认识到溶血隐秘杆菌是免疫功能正常患者的全身性致病病原体很重要。

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Clinically Infrequent Arcanobacterium haemolyticum Bacteremia Complicated by Foot Decubitus Ulcer: An Educational Reminder for Primary Care Physicians.临床罕见的溶血隐秘杆菌菌血症并发足部压疮溃疡:给基层医疗医生的警示
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[Fatal sepsis due to an emerging bacteria: Arcanobacterium hemolyticum].[由一种新出现的细菌——溶血隐秘杆菌引起的致命性败血症]
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Clinical characteristics, treatment and efficacy of calcaneal osteomyelitis: a systematic review with synthesis analysis of 1118 reported cases.跟骨骨髓炎的临床特征、治疗及疗效:对1118例报告病例进行综合分析的系统评价
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本文引用的文献

1
Not just a simple sore throat.
Acute Med. 2017;16(3):145-148.
2
Haemolytic differential identification of isolated from a patient with diabetic foot ulcers.从一名糖尿病足溃疡患者分离出的溶血鉴别
JMM Case Rep. 2016 Feb 12;3(1):e005016. doi: 10.1099/jmmcr.0.005016. eCollection 2016 Feb.
3
Bacteriological characteristics of Arcanobacterium haemolyticum isolated from seven patients with skin and soft-tissue infections.从7例皮肤和软组织感染患者中分离出的溶血隐秘杆菌的细菌学特征。
J Med Microbiol. 2015 Apr;64(Pt 4):369-374. doi: 10.1099/jmm.0.000038. Epub 2015 Feb 9.
4
Arcanobacterium haemolyticum osteomyelitis and sepsis: a diagnostic conundrum.海洋分枝杆菌骨髓炎和败血症:诊断难题。
Surg Infect (Larchmt). 2013 Jun;14(3):322-4. doi: 10.1089/sur.2011.129. Epub 2013 Apr 12.
5
Infective endocarditis caused by Arcanobacterium haemolyticum: a case report.溶血隐秘杆菌引起的感染性心内膜炎:一例报告。
Ann Clin Microbiol Antimicrob. 2011 May 12;10:17. doi: 10.1186/1476-0711-10-17.
6
Lemierre's syndrome and septicaemia caused solely by Arcanobacterium haemolyticum in a young immunocompetent patient.一名年轻免疫功能正常患者仅由溶血隐秘杆菌引起的勒米尔综合征和败血症。
J Med Microbiol. 2009 Dec;58(Pt 12):1645-1648. doi: 10.1099/jmm.0.007492-0. Epub 2009 Aug 6.
7
Severe sepsis caused by Arcanobacterium haemolyticum: a case report and review of the literature.溶血隐秘杆菌引起的严重脓毒症:一例病例报告及文献复习
Ann Pharmacother. 2008 Nov;42(11):1697-702. doi: 10.1345/aph.1L294. Epub 2008 Sep 23.
8
Arcanobacterium haemolyticum bacteraemia and soft-tissue infections: case report and review of the literature.溶血隐秘杆菌菌血症及软组织感染:病例报告与文献综述
J Infect. 2006 Aug;53(2):e69-74. doi: 10.1016/j.jinf.2005.10.008. Epub 2005 Nov 28.
9
Arcanobacterium haemolyticum sinusitis and orbital cellulitis.溶血隐秘杆菌性鼻窦炎和眼眶蜂窝织炎。
Pediatr Infect Dis J. 2003 May;22(5):465-7.
10
Three cases of Arcanobacterium haemolyticum associated with abscess formation and cellulitis.三例溶血隐秘杆菌感染伴脓肿形成和蜂窝织炎。
Eur J Clin Microbiol Infect Dis. 1999 Nov;18(11):804-6. doi: 10.1007/s100960050404.