Infante Jose Rafael, García Lucía, Rayo Juan Ignacio, Serrano Justo, Moreno Manuel, Cobo Amparo, Jimenez Pedro, Martínez Andrés
Department of Nuclear Medicine, Hospital Infanta Cristina, Badajoz, Spain.
Indian J Nucl Med. 2019 Jan-Mar;34(1):66-68. doi: 10.4103/ijnm.IJNM_120_18.
The POEMS syndrome is a rare and multisystemic disease characterized by the presence of polyneuropathy, organomegaly, endocrinopathy, presence of M protein, and alterations in the skin. The existence of bone lesions is frequent, being generally blastic or mixed and rarely lytic. We present the case of a 54-year-old male patient diagnosed with POEMS syndrome, with atypical presence of lytic lesions, who was referred for an 18F-fluorodeoxyglucose positron emission tomography-computed tomography (PET-CT) study for initial staging of the process. There were several hypermetabolic foci coinciding with bone lesions, reaching a maximum standardized uptake value of 15 at the level of the right iliac bone with associated soft-tissue mass. PET-CT is an adequate tool for evaluation, diagnosis, and monitoring of the pathology. The scan allows the detection and selection for its biopsy of bone lesions and lymphadenopathies.
POEMS综合征是一种罕见的多系统疾病，其特征为多发性神经病、器官肿大、内分泌病、M蛋白血症以及皮肤改变。骨病变很常见，通常为成骨型或混合型，很少为溶骨型。我们报告一例54岁男性患者，诊断为POEMS综合征，伴有非典型溶骨病变，因该疾病的初始分期接受了18F-氟脱氧葡萄糖正电子发射断层扫描-计算机断层扫描（PET-CT）检查。有几个高代谢灶与骨病变相符，右侧髂骨处最大标准化摄取值达到15，并伴有软组织肿块。PET-CT是评估、诊断和监测该疾病的合适工具。该扫描可检测骨病变和淋巴结病并选择进行活检。
