Ministry of Education Key Laboratory of Integrated Regulation and Resource Development on Shallow Lakes, College of Environment, Hohai University, Xikang Road No. 1, Nanjing, Jiangsu, 210098, People's Republic of China.
College of Water Conservancy and Civil Engineering, Shandong Agricultural University, Daizong Road No.61, Tai'an, Shandong, 271018, People's Republic of China.
Environ Sci Pollut Res Int. 2019 Mar;26(9):9184-9192. doi: 10.1007/s11356-019-04279-y. Epub 2019 Feb 4.
Large quantities of antibiotics are manufactured, used, and eventually discharged into alga-containing water environment as prototypes, by-products, or transformation products. Different activities of Chlamydomonas reinhardtii toward cefradine (CFD) were studied, and the results indicated that CFD is resistant (removal rate of 5.45-14.72%) in simulated natural water environment. Cefradine was mainly removed by hydrolysis, adsorption, desorption, photodecarboxylation, and photoisomerization. The effects of C. reinhardtii density, initial solution pH, and different light sources on CFD removal efficiency were investigated. The optimum conditions occurred at a density of algae 10 × 10 cells/mL, a solution pH of 9.0, and the ultraviolet (UV) light. Additionally, the removal kinetics under 16 different conditions was explored. The results showed that the removal of CFD fits well with a pseudo-first-order kinetic, and the half-life times are from 0.8 to 261.6 days. This study summarizes the CFD removal mechanisms in alga-containing water environment, highlights the important role played by light irradiation in eliminating CFD, and obtains the important kinetic data on CFD removal.
大量抗生素作为原型、副产物或转化产物被制造、使用，最终排放到含有藻类的水环境中。本研究考察了莱茵衣藻（Chlamydomonas reinhardtii）对头孢拉定（CFD）的不同活性，结果表明在模拟天然水环境中，CFD 具有抗性（去除率为 5.45-14.72%）。头孢拉定主要通过水解、吸附、解吸、光脱羧和光异构化去除。考察了莱茵衣藻密度、初始溶液 pH 值和不同光源对 CFD 去除效率的影响。最佳条件为藻类密度为 10×10 个细胞/mL、溶液 pH 值为 9.0 和紫外线（UV）光。此外，还探索了 16 种不同条件下的去除动力学。结果表明，CFD 的去除符合准一级动力学，半衰期为 0.8 至 261.6 天。本研究总结了含有藻类的水环境中 CFD 的去除机制，强调了光照在消除 CFD 方面的重要作用，并获得了 CFD 去除的重要动力学数据。
