Ohtahara S
Department of Child Neurology, Okayama University Medical School, Japan.
Jpn J Psychiatry Neurol. 1988 Sep;42(3):535-42. doi: 10.1111/j.1440-1819.1988.tb01349.x.
The Lennox-Gastaut syndrome is the biggest target of current epilepsy research, and it contains almost all the fundamental problems in epilepsy. Highly different terms were given to the relatively broad area of the Lennox-Gastaut syndrome by many schools hitherto. But gradually a general outline of this syndrome has been defined and the name Lennox-Gastaut syndrome has been internationally fixed, leading to the holding of the International Symposium at Bad Kreuznach in 1987. Although the Lennox-Gastaut syndrome is a clinico-electrical entity which is clearly defined both clinically and electroencephalographically, diagnostic boundaries are not always precise in individual cases. According to the clinico-electroencephalographic investigation on typical and atypical cases, diagnostic guidelines of the Lennox-Gastaut syndrome were presented in this paper. Etiology and classification of the Lennox-Gastaut syndrome were also mentioned referring to the significance of idiopathic Lennox-Gastaut syndrome.
Lennox-Gastaut综合征是当前癫痫研究的最大目标,它几乎涵盖了癫痫的所有基本问题。迄今为止,许多学派针对Lennox-Gastaut综合征这一相对宽泛的领域给出了截然不同的术语。但该综合征的总体轮廓已逐渐明确,“Lennox-Gastaut综合征”这一名称也在国际上固定下来,从而促成了1987年在巴特克罗伊茨纳赫召开的国际研讨会。尽管Lennox-Gastaut综合征是一个临床-电生理实体,在临床和脑电图方面都有明确界定,但在个别病例中诊断界限并不总是精确的。根据对典型和非典型病例的临床-脑电图研究,本文提出了Lennox-Gastaut综合征的诊断指南。文中还提及了Lennox-Gastaut综合征的病因和分类,并阐述了特发性Lennox-Gastaut综合征的意义。