Ikonomoff S I
MMW Munch Med Wochenschr. 1978 Jun 30;120(26):905-8.
Substitution therapy with thiamine, ATP and magnesium which, just like that with clomethiazole has a parasympathomimetic action, is based on the principle of suppression of the sympathetic system. If these patients are no longer capable for any reason of continuing to take the endogenous substances (thiamine, ATP and magnesium) by mouth, the treatment is continued with clomethiazole an an infusion. But since the intravenous administration of clomethiazole is not seldom accompanied by a parasympathetic coma with respiratory and cardiac depression and miosis, treatment of a sympathetic blockade with dextrose solution containing salt is proposed.
硫胺素、三磷酸腺苷和镁的替代疗法，就像氯美噻唑的替代疗法一样具有拟副交感神经作用，其基于抑制交感神经系统的原理。如果这些患者由于任何原因无法继续口服内源性物质（硫胺素、三磷酸腺苷和镁），则继续使用氯美噻唑进行静脉输注治疗。但是，由于静脉注射氯美噻唑常常伴有副交感神经昏迷，并伴有呼吸和心脏抑制以及瞳孔缩小，因此建议用含盐水的葡萄糖溶液治疗交感神经阻滞。
