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First Complete Genome Sequence of a Simian Foamy Virus Infecting the Neotropical Primate Brachyteles arachnoides.感染新热带灵长类动物绒毛蛛猴的猿泡沫病毒的首个全基因组序列
Microbiol Resour Announc. 2018 Jul 19;7(2). doi: 10.1128/MRA.00839-18. eCollection 2018 Jul.
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Potent neutralizing antibodies in humans infected with zoonotic simian foamy viruses target conserved epitopes located in the dimorphic domain of the surface envelope protein.在感染动物源性泡沫病毒的人类中发现的强效中和抗体针对位于表面包膜蛋白二聚体结构域中的保守表位。
PLoS Pathog. 2018 Oct 8;14(10):e1007293. doi: 10.1371/journal.ppat.1007293. eCollection 2018 Oct.
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The chromatin binding domain, including the QPQRYG motif, of feline foamy virus Gag is required for viral DNA integration and nuclear accumulation of Gag and the viral genome.猫科泡沫病毒 Gag 的染色质结合域,包括 QPQRYG 基序,是病毒 DNA 整合和 Gag 及病毒基因组的核积累所必需的。
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Replacement of feline foamy virus bet by feline immunodeficiency virus vif yields replicative virus with novel vaccine candidate potential.用猫免疫缺陷病毒 vif 替代猫泡沫病毒 bet 产生具有新型疫苗候选潜力的复制病毒。
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Clinical Signs and Blood Test Results Among Humans Infected With Zoonotic Simian Foamy Virus: A Case-Control Study.人类感染动物源性泡沫病毒的临床症状和血液检测结果:病例对照研究。
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8
Spumaretroviruses: Updated taxonomy and nomenclature.泡沫反转录病毒:更新的分类和命名法。
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A non-invasive specimen collection method and a novel simian foamy virus (SFV) DNA quantification assay in New World primates reveal aspects of tissue tropism and improved SFV detection.一种用于新大陆灵长类动物的非侵入性样本采集方法和一种新型猿泡沫病毒(SFV)DNA定量检测方法,揭示了组织嗜性方面的情况并改进了SFV检测。
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第十二届国际泡沫病毒会议-会议报告。

Twelfth International Foamy Virus Conference-Meeting Report.

机构信息

Institut für Experimentelle Gentherapie und Tumorforschung, Universitätsmedizin Rostock, 18057 Rostock, Germany.

Department of Viral Transformation Mechanisms, Research Program Infection, Inflammation and Cancer, 69120 Heidelberg, Germany.

出版信息

Viruses. 2019 Feb 1;11(2):134. doi: 10.3390/v11020134.

DOI:10.3390/v11020134
PMID:30717288
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6409691/
Abstract

The 12 International Foamy Virus Conference took place on August 30⁻31, 2018 at the Technische Universität Dresden, Dresden, Germany. The meeting included presentations on current research on non-human primate and non-primate foamy viruses (FVs; also called spumaretroviruses) as well as keynote talks on related research areas in retroviruses. The taxonomy of foamy viruses was updated earlier this year to create five new genera in the subfamily, , based on their animal hosts. Research on viruses from different genera was presented on topics of potential relevance to human health, such as natural infections and cross-species transmission, replication, and viral-host interactions in particular with the immune system, dual retrovirus infections, virus structure and biology, and viral vectors for gene therapy. This article provides an overview of the current state-of-the-field, summarizes the meeting highlights, and presents some important questions that need to be addressed in the future.

摘要

第十二届国际泡沫病毒会议于 2018 年 8 月 30 日至 31 日在德国德累斯顿工业大学举行。会议包括有关非人类灵长类动物和非灵长类动物泡沫病毒(也称为泡沫反转录病毒)的当前研究报告,以及关于反转录病毒相关研究领域的主题演讲。今年早些时候,泡沫病毒的分类法进行了更新,根据其动物宿主创建了五个新属,在亚科中。关于不同属病毒的研究涉及与人类健康相关的潜在主题,例如自然感染和跨物种传播、复制以及病毒与免疫系统的相互作用,双重反转录病毒感染、病毒结构和生物学以及用于基因治疗的病毒载体。本文概述了该领域的最新进展,总结了会议要点,并提出了未来需要解决的一些重要问题。