Molina Adolfo L, Magruder Teresa G, Aban Inmaculada B, Ward Lauren, Narayanan Sridaran, Walley Susan C
Department of Pediatrics, School of Medicine and
Department of Pediatrics, School of Medicine and.
Hosp Pediatr. 2019 Mar;9(3):194-200. doi: 10.1542/hpeds.2017-0239. Epub 2019 Feb 4.
Asthma is a common cause of pediatric hospitalization. Nonadherence to asthma medications is associated with worse outcomes; however, there is a paucity of data regarding posthospitalization prescription filling and hospital reuse. Our objective was to identify patients at risk for hospital reuse after being hospitalized for asthma.
This is a retrospective study of patients with asthma who were discharged from a children's hospital in which we use Medicaid claims data to evaluate prescription fills within 30 days and 12 months. Chart reviews were used for demographics, chronic asthma severity, admission severity, and hospital reuse. and χ tests were performed for continuous and categorical variables. A generalized linear mixed model was fitted to predict the odds of hospital reuse, which was defined as requiring an emergency department visit or rehospitalization. Survival analysis using log-rank testing was used for modeling the time to hospital reuse.
Fifty-four percent of patients discharged with asthma had hospital reuse within 1 year of discharge. There was no association between hospital reuse and prescription filling for systemic steroids (odds ratio [OR] 1.30; confidence interval [CI]: 0.85-2.00; = .21) or controller medications (OR 1.5; CI: 0.92-2.52; = .10). There was a higher number of controller and systemic steroid prescription fills over 12 months for patients with hospital reuse. The factors associated with greater odds of hospital reuse were severity of chronic asthma diagnosis ( = .03) as well as African American race (OR 1.92; CI: 1.17-3.13; = .01).
For Medicaid-insured patients discharged with asthma, worse chronic asthma severity and African American race were associated with greater odds of hospital reuse. Decreased prescription filling was not associated with greater odds of hospital reuse.
哮喘是儿童住院的常见原因。不坚持使用哮喘药物与更差的预后相关;然而,关于出院后处方配药和再次住院的数据却很匮乏。我们的目的是确定哮喘住院后有再次住院风险的患者。
这是一项对一家儿童医院出院的哮喘患者的回顾性研究,我们使用医疗补助索赔数据来评估30天内和12个月内的处方配药情况。通过查阅病历获取人口统计学信息、慢性哮喘严重程度、入院严重程度和再次住院情况。对连续变量和分类变量进行t检验和卡方检验。采用广义线性混合模型来预测再次住院的几率,再次住院定义为需要急诊就诊或再次住院。使用对数秩检验的生存分析用于对再次住院时间进行建模。
54%的哮喘出院患者在出院1年内再次住院。再次住院与全身用类固醇药物的处方配药(比值比[OR]为1.30;置信区间[CI]:0.85 - 2.00;P = 0.21)或控制药物(OR为1.5;CI:0.92 - 2.52;P = 0.10)之间无关联。再次住院的患者在12个月内的控制药物和全身用类固醇药物处方配药数量更多。与再次住院几率较高相关的因素是慢性哮喘诊断的严重程度(P = 0.03)以及非裔美国人种族(OR为1.92;CI:1.17 - 3.13;P = 0.01)。
对于因哮喘出院的医疗补助参保患者,慢性哮喘严重程度较差和非裔美国人种族与再次住院几率较高相关。处方配药减少与再次住院几率较高无关。