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单次曝光无运动的快速 X 射线差分相位衬度成像。

Fast X-ray Differential Phase Contrast Imaging with One Exposure and without Movements.

机构信息

Research Center of Digital Radiation Imaging and Biomedical Imaging, Beihang University, Beijing, 100191, China.

School of Mechanical Engineering and Automation, Beihang University, Beijing, 100191, China.

出版信息

Sci Rep. 2019 Feb 4;9(1):1113. doi: 10.1038/s41598-018-37687-0.

DOI:10.1038/s41598-018-37687-0
PMID:30718674
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6361880/
Abstract

Grating interferometry X-ray differential phase contrast imaging (GI-XDPCI) has provided enhanced imaging contrast and attracted more and more interests. Currently the low imaging efficiency and increased dose remain to be the bottlenecks in the engineering applications of GI-XDPCI. Different from the widely-used X-ray absorption contrast imaging (XACI) found in hospitals and factories, GI-XDPCI involves a grating stepping procedure that is time-consuming and leads to a significantly increased X-ray exposure time. In this paper, we report a fast GI-XDPCI method without movements by designing a new absorption grating. There is no grating stepping in this approach, and all components remain stationary during the imaging. Three kinds of imaging contrasts are provided with greatly reduced time. This work is comprised of a numerical study of the method and its verification using a sub-set of the dataset measured with a standard GI-XDPCI system at the beam line BL13W1 of the Shanghai Synchrotron Radiation Facility (SSRF). These results have validated the presented method.

摘要

光栅干涉 X 射线差分相位衬度成像(GI-XDPCI)提供了增强的成像对比度,引起了越来越多的关注。目前,成像效率低和剂量增加仍然是 GI-XDPCI 工程应用中的瓶颈。与医院和工厂中广泛使用的 X 射线吸收对比度成像(XACI)不同,GI-XDPCI 涉及到一个耗时的光栅步进过程,导致 X 射线曝光时间显著增加。在本文中,我们通过设计一种新的吸收光栅报告了一种无需运动的快速 GI-XDPCI 方法。在该方法中没有光栅步进,并且在成像过程中所有组件都保持静止。三种成像对比度大大减少了时间。这项工作包括对该方法的数值研究及其在上海同步辐射装置(SSRF)BL13W1 光束线的标准 GI-XDPCI 系统测量的数据集的子集上的验证。这些结果验证了所提出的方法。

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本文引用的文献

1
Qualitative and Quantitative Evaluation of Structural Myocardial Alterations by Grating-Based Phase-Contrast Computed Tomography.基于光栅相位对比计算机断层扫描的心肌结构改变的定性和定量评估。
Invest Radiol. 2018 Jan;53(1):26-34. doi: 10.1097/RLI.0000000000000408.
2
Grating-based phase-contrast and dark-field computed tomography: a single-shot method.光栅相位对比和暗场计算机断层扫描:单次拍摄方法。
Sci Rep. 2017 Aug 7;7(1):7476. doi: 10.1038/s41598-017-06729-4.
3
Large field of view, fast and low dose multimodal phase-contrast imaging at high x-ray energy.
在高 X 射线能量下实现大视野、快速、低剂量的多模态相衬成像。
Sci Rep. 2017 May 19;7(1):2187. doi: 10.1038/s41598-017-02412-w.
4
Qualitative and Quantitative Imaging Evaluation of Renal Cell Carcinoma Subtypes with Grating-based X-ray Phase-contrast CT.基于光栅射线相衬 CT 的肾癌亚型的定性与定量成像评估。
Sci Rep. 2017 Mar 31;7:45400. doi: 10.1038/srep45400.
5
Mass Density Measurement of Mineralized Tissue with Grating-Based X-Ray Phase Tomography.基于光栅的X射线相断层扫描技术对矿化组织的质量密度测量
PLoS One. 2016 Dec 21;11(12):e0167797. doi: 10.1371/journal.pone.0167797. eCollection 2016.
6
Hard X-ray phase-contrast tomography of non-homogeneous specimens: grating interferometry versus propagation-based imaging.非均匀样本的硬X射线相衬断层扫描:光栅干涉测量法与基于传播的成像方法对比
J Synchrotron Radiat. 2016 Sep 1;23(Pt 5):1202-9. doi: 10.1107/S1600577516009164. Epub 2016 Jul 26.
7
Asymmetric masks for laboratory-based X-ray phase-contrast imaging with edge illumination.基于边缘照明的实验室 X 射线相衬成像用不对称掩模。
Sci Rep. 2016 May 5;6:25466. doi: 10.1038/srep25466.
8
Helical X-ray phase-contrast computed tomography without phase stepping.无相位步进的螺旋X射线相衬计算机断层扫描
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