单次曝光无运动的快速 X 射线差分相位衬度成像。

Fast X-ray Differential Phase Contrast Imaging with One Exposure and without Movements.

机构信息

Research Center of Digital Radiation Imaging and Biomedical Imaging, Beihang University, Beijing, 100191, China.

School of Mechanical Engineering and Automation, Beihang University, Beijing, 100191, China.

出版信息

Sci Rep. 2019 Feb 4;9(1):1113. doi: 10.1038/s41598-018-37687-0.

DOI:10.1038/s41598-018-37687-0

PMID:30718674

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6361880/

Abstract

Grating interferometry X-ray differential phase contrast imaging (GI-XDPCI) has provided enhanced imaging contrast and attracted more and more interests. Currently the low imaging efficiency and increased dose remain to be the bottlenecks in the engineering applications of GI-XDPCI. Different from the widely-used X-ray absorption contrast imaging (XACI) found in hospitals and factories, GI-XDPCI involves a grating stepping procedure that is time-consuming and leads to a significantly increased X-ray exposure time. In this paper, we report a fast GI-XDPCI method without movements by designing a new absorption grating. There is no grating stepping in this approach, and all components remain stationary during the imaging. Three kinds of imaging contrasts are provided with greatly reduced time. This work is comprised of a numerical study of the method and its verification using a sub-set of the dataset measured with a standard GI-XDPCI system at the beam line BL13W1 of the Shanghai Synchrotron Radiation Facility (SSRF). These results have validated the presented method.

摘要

光栅干涉 X 射线差分相位衬度成像（GI-XDPCI）提供了增强的成像对比度，引起了越来越多的关注。目前，成像效率低和剂量增加仍然是 GI-XDPCI 工程应用中的瓶颈。与医院和工厂中广泛使用的 X 射线吸收对比度成像（XACI）不同，GI-XDPCI 涉及到一个耗时的光栅步进过程，导致 X 射线曝光时间显著增加。在本文中，我们通过设计一种新的吸收光栅报告了一种无需运动的快速 GI-XDPCI 方法。在该方法中没有光栅步进，并且在成像过程中所有组件都保持静止。三种成像对比度大大减少了时间。这项工作包括对该方法的数值研究及其在上海同步辐射装置（SSRF）BL13W1 光束线的标准 GI-XDPCI 系统测量的数据集的子集上的验证。这些结果验证了所提出的方法。