Schiessel R, Vattay P
I. Chirurgische Universitätsklinik, Wien.
Wien Klin Wochenschr. 1988 Nov 4;100(21):693-9.
Endogenous prostaglandins are involved in several gastrointestinal diseases such as peptic ulcer. Crohn's disease, ulcerative colitis and radiation enteritis, although a casual role has not been proven in any condition. At present therapeutic indications are confined to the treatment of peptic ulcer with synthetic analogues at a dosage which inhibits acid secretion.
内源性前列腺素参与多种胃肠道疾病,如消化性溃疡、克罗恩病、溃疡性结肠炎和放射性肠炎,尽管尚未在任何一种疾病中证实其因果关系。目前,治疗适应证仅限于使用合成类似物以抑制胃酸分泌的剂量治疗消化性溃疡。