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肺结节状淋巴组织增生。

Pulmonary Nodular Lymphoid Hyperplasia.

机构信息

From the Department of Pathology, Anatomy and Laboratory Medicine, West Virginia University, Morgantown (Dr Yell); and the Department of Pathology, University of Texas Southwestern Biocenter, Dallas (Dr Rosado).

出版信息

Arch Pathol Lab Med. 2019 Sep;143(9):1149-1153. doi: 10.5858/arpa.2018-0188-RS. Epub 2019 Feb 6.

Abstract

Pulmonary nodular lymphoid hyperplasia is an uncommon reactive lymphoproliferative disorder that presents as an asymptomatic lung mass. The histopathologic diagnosis of pulmonary nodular lymphoid hyperplasia may be challenging because of its morphologic overlap with other diseases, such as extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue and immunoglobulin G4-related sclerosing disease. Despite the similarities, there are distinctive morphologic and phenotypic features that allow for the correct diagnosis in the majority of cases. This review aims to discuss the clinicopathologic features of pulmonary nodular lymphoid hyperplasia and contrast them with its histopathologic mimickers.

摘要

肺结节状淋巴组织增生是一种不常见的反应性淋巴增生性疾病,表现为无症状的肺部肿块。由于其形态学与其他疾病(如黏膜相关淋巴组织结外边缘区淋巴瘤和 IgG4 相关硬化性疾病)重叠,肺结节状淋巴组织增生的组织病理学诊断可能具有挑战性。尽管存在相似之处,但仍存在独特的形态学和表型特征,可在大多数情况下做出正确诊断。本文旨在讨论肺结节状淋巴组织增生的临床病理特征,并将其与组织病理学类似物进行对比。

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