Luesley D, Cullimore J
Department of Obstetrics and Gynaecology, University of Birmingham, UK.
Cancer Surv. 1988;7(3):529-45.
Treatment of cervical intraepithelial neoplasia, both squamous and glandular, is based on the premise that this condition may ultimately progress to invasive cancer. Treatments have evolved in a conservative direction resulting in reduced morbidity yet also achieving satisfactory control of disease. As yet there is no way in which those cases that have malignant potential can be distinguished from those that do not. Satisfactory management is dependent upon the exclusion of an invasive process. Cytologic, colposcopic and histologic confirmation of preinvasion are therefore natural precedents to management.
宫颈上皮内瘤变（包括鳞状和腺性）的治疗基于这样一个前提，即这种情况最终可能发展为浸润性癌。治疗方法已朝着保守方向发展，在降低发病率的同时也实现了对疾病的满意控制。然而，目前尚无方法区分那些具有恶性潜能的病例和不具有恶性潜能的病例。满意的治疗取决于排除浸润性病变。因此，在进行治疗之前，自然需要通过细胞学、阴道镜检查和组织学检查来确认癌前病变。
