Allahverdian V, Valaitis J, Kalis O, Pearlman S
J Reprod Med. 1980 Jan;24(1):1-4.
One hundred consecutive outpatients seen in the colposcopy clinic of a private hospital had one or more Papanicolaou smears that suggested cervical atypia, dysplasia or carcinoma in situ. Of these 100 patients, 7% underwent a diagnostic cervical cone biopsy; 11% more had therapeutic conization. The accuracy of colposcopic examination with directed cervical biopsy within one level (under or over) of histologic findings was 88%; the cytologic accuracy within one level of histologic findings was 83%. The study showed that patients with cervical atypia at cytologic examination had dysplasia and carcinoma in situ at subsequent colposcopic cervical examination with directed biopsy.
在一家私立医院的阴道镜诊所就诊的100例连续门诊患者，其一张或多张巴氏涂片提示宫颈非典型增生、发育异常或原位癌。在这100例患者中，7%接受了诊断性宫颈锥切活检；另有11%接受了治疗性锥切术。阴道镜检查结合在组织学检查结果一级（高于或低于）范围内的定向宫颈活检的准确率为88%；在组织学检查结果一级范围内的细胞学准确率为83%。该研究表明，细胞学检查显示宫颈非典型增生的患者在随后的阴道镜宫颈检查及定向活检中存在发育异常和原位癌。
