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发育生物学:随波逐流,保持身体笔直。

Developmental Biology: Go with the Flow to Keep the Body Straight.

机构信息

Institute of Molecular Biology, Department of Biology, University of Oregon, Eugene, OR 97403, USA.

出版信息

Curr Biol. 2019 Feb 4;29(3):R101-R103. doi: 10.1016/j.cub.2018.12.011.

DOI:10.1016/j.cub.2018.12.011
PMID:30721676
Abstract

It has long been noticed that zebrafish defective in ciliary beating develop abnormal body curvatures. Recently, insights into how cilia keep the body straight have emerged, with implications for understanding human scoliosis.

摘要

长期以来,人们注意到,纤毛运动有缺陷的斑马鱼会出现身体弯曲的异常。最近,人们对纤毛如何保持身体笔直有了新的认识,这对理解人类脊柱侧凸症具有启示意义。

相似文献

1
Developmental Biology: Go with the Flow to Keep the Body Straight.发育生物学:随波逐流,保持身体笔直。
Curr Biol. 2019 Feb 4;29(3):R101-R103. doi: 10.1016/j.cub.2018.12.011.
2
On being the right shape: Roles for motile cilia and cerebrospinal fluid flow in body and spine morphology.关于正确形态:运动性纤毛和脑脊液流动在身体及脊柱形态形成中的作用。
Semin Cell Dev Biol. 2021 Feb;110:104-112. doi: 10.1016/j.semcdb.2020.07.005. Epub 2020 Jul 18.
3
Ccdc57 is required for straightening the body axis by regulating ciliary motility in the brain ventricle of zebrafish.Ccdc57 通过调节斑马鱼脑室中的纤毛运动来矫正身体轴。
J Genet Genomics. 2023 Apr;50(4):253-263. doi: 10.1016/j.jgg.2022.12.007. Epub 2023 Jan 18.
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Characterization of Endothelial Cilia Distribution During Cerebral-Vascular Development in Zebrafish ( Danio rerio).斑马鱼(Danio rerio)脑血管发育过程中内皮纤毛的分布特征。
Arterioscler Thromb Vasc Biol. 2018 Dec;38(12):2806-2818. doi: 10.1161/ATVBAHA.118.311231.
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From cilia hydrodynamics to zebrafish embryonic development.从纤毛水动力学到斑马鱼胚胎发育。
Curr Top Dev Biol. 2011;95:33-66. doi: 10.1016/B978-0-12-385065-2.00002-5.
6
Ciliary Beating Compartmentalizes Cerebrospinal Fluid Flow in the Brain and Regulates Ventricular Development.纤毛摆动将脑脊髓液在脑中分隔开,并调节脑室发育。
Curr Biol. 2019 Jan 21;29(2):229-241.e6. doi: 10.1016/j.cub.2018.11.059. Epub 2019 Jan 3.
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nlz1 is required for cilia formation in zebrafish embryogenesis.Nlz1是斑马鱼胚胎发育中纤毛形成所必需的。
Dev Biol. 2015 Oct 15;406(2):203-11. doi: 10.1016/j.ydbio.2015.08.019. Epub 2015 Aug 29.
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A function for the Joubert syndrome protein Arl13b in ciliary membrane extension and ciliary length regulation.Joubert 综合征蛋白 Arl13b 在纤毛膜延伸和纤毛长度调节中的功能。
Dev Biol. 2015 Jan 15;397(2):225-36. doi: 10.1016/j.ydbio.2014.11.009. Epub 2014 Nov 20.
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Measurement of ciliary beating and fluid flow in the zebrafish adult telencephalon.斑马鱼成体端脑纤毛摆动和液体流动的测量。
STAR Protoc. 2022 Sep 16;3(3):101542. doi: 10.1016/j.xpro.2022.101542. Epub 2022 Jul 16.
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Motile-Cilia-Mediated Flow Improves Sensitivity and Temporal Resolution of Olfactory Computations.纤毛运动介导的流动可提高嗅觉计算的灵敏度和时间分辨率。
Curr Biol. 2017 Jan 23;27(2):166-174. doi: 10.1016/j.cub.2016.11.036. Epub 2016 Dec 29.

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C-mannosyltransferase DPY19L1L-mediated Reissner Fiber formation is critical for zebrafish () body axis straightening.C-甘露糖基转移酶DPY19L1L介导的Reissner纤维形成对斑马鱼体轴伸直至关重要。
Sci Adv. 2025 May 9;11(19):eadv2032. doi: 10.1126/sciadv.adv2032.
2
Advances in genetic factors of adolescent idiopathic scoliosis: a bibliometric analysis.青少年特发性脊柱侧凸遗传因素的研究进展:一项文献计量学分析
Front Pediatr. 2024 Jan 3;11:1301137. doi: 10.3389/fped.2023.1301137. eCollection 2023.
3
Brain asymmetry is globally different in males and females: exploring cortical volume, area, thickness, and mean curvature.
男性和女性的大脑左右不对称存在全球差异:探索皮质体积、面积、厚度和平均曲率。
Cereb Cortex. 2023 Dec 9;33(24):11623-11633. doi: 10.1093/cercor/bhad396.
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Urotensin II-related peptides, Urp1 and Urp2, control zebrafish spine morphology.Urotensin II 相关肽,Urp1 和 Urp2,控制斑马鱼脊柱形态。
Elife. 2022 Dec 1;11:e83883. doi: 10.7554/eLife.83883.
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Turning the Curve Into Straight: Phenogenetics of the Spine Morphology and Coordinate Maintenance in the Zebrafish.化曲为直:斑马鱼脊柱形态与坐标维持的表型遗传学
Front Cell Dev Biol. 2022 Jan 26;9:801652. doi: 10.3389/fcell.2021.801652. eCollection 2021.
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Development of a straight vertebrate body axis.脊椎动物体轴的直向发育。
Development. 2020 Oct 6;147(21):dev175794. doi: 10.1242/dev.175794.
7
The role of motile cilia in the development and physiology of the nervous system.纤毛在神经系统发育和生理学中的作用。
Philos Trans R Soc Lond B Biol Sci. 2020 Feb 17;375(1792):20190156. doi: 10.1098/rstb.2019.0156. Epub 2019 Dec 30.
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Making and breaking symmetry in development, growth and disease.在发育、生长和疾病中形成和打破对称。
Development. 2019 Aug 15;146(16):dev170985. doi: 10.1242/dev.170985.