Lachman M F, Vogel E H, Kim K
Department of Pathology, Medical College of Ohio, Toledo 43699.
Diagn Cytopathol. 1988;4(2):121-4. doi: 10.1002/dc.2840040208.
The cytologic features of familial hemophagocytic lymphohistiocytosis in two infant siblings were reviewed and compared to the histopathologic features in the same cases. The cytologic features of familial hemophagocytic lymphohistiocytosis in imprint smears from the spleen, lymph nodes, and liver were distinct, with proliferation of benign histiocytes engulfing erythrocytes and platelets. Hemophagocytic activity was more readily identifiable in imprint smears than in paraffin-embedded histologic sections. The differential diagnosis of histiocytic proliferative syndromes is also discussed.
回顾了两名婴儿同胞家族性噬血细胞性淋巴组织细胞增生症的细胞学特征，并与同一病例的组织病理学特征进行了比较。脾脏、淋巴结和肝脏印片涂片中家族性噬血细胞性淋巴组织细胞增生症的细胞学特征明显，可见良性组织细胞增生并吞噬红细胞和血小板。与石蜡包埋的组织学切片相比，印片涂片中更容易识别噬血活性。文中还讨论了组织细胞增生综合征的鉴别诊断。
