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[与正常人胃黏膜抗原免疫相关的可移植细胞抗原]

[The antigen of transplantable cells immunologically related to the antigen of the normal human gastric mucosa].

作者信息

Bobrova T S, Kriukova I N, Chuev Iu V, Rotenberg V I, Golovkina T V

出版信息

Eksp Onkol. 1988;10(6):35-9.

PMID:3072175
Abstract

A newly detected antigen common for transplantable HeLa-like cell lines and human gastric mucosa has been revealed in all parts of the stomach and in highly differentiated gastric adenocarcinomas in humans. It is localized in the basal area of tall columnar cells in the mucosa and has one immunologically active subunit with molecular weight of 39 kDa. The antigen differs from the other earlier described gastrointestinal antigens in its localization in the organs and cells and in other characteristics.

摘要

在人胃的所有部位以及高分化胃腺癌中,发现了一种新检测到的、可移植的类HeLa细胞系和人胃黏膜共有的抗原。它定位于黏膜中高柱状细胞的基底区域,具有一个分子量为39 kDa的免疫活性亚基。该抗原在其在器官和细胞中的定位以及其他特征方面,与先前描述的其他胃肠道抗原不同。

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