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神经节细胞复合体分析作为特发性颅内高压早期神经元丢失的潜在指标

Ganglion Cell Complex Analysis as a Potential Indicator of Early Neuronal Loss in Idiopathic Intracranial Hypertension.

作者信息

Athappilly Geetha, García-Basterra Ignacio, Machado-Miller Flavia, Hedges Thomas R, Mendoza-Santiesteban Carlos, Vuong Laurel

机构信息

The New England Eye Center, Tufts Medical Center, Boston, Massachusetts, USA.

Department of Ophthalmology, Lahey Clinic, Burlington, Massachusetts, USA.

出版信息

Neuroophthalmology. 2018 Jun 19;43(1):10-17. doi: 10.1080/01658107.2018.1476558. eCollection 2019 Feb.

DOI:10.1080/01658107.2018.1476558
PMID:30723519
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6351016/
Abstract

Reliable visual field testing is the gold standard in identifying future vision loss in patients with Idiopathic Intracranial hypertension (IIH). However, when field performance is unreliable, GCC analysis may be useful. We evaluated IIH patients over three visits: initial visit, follow-up visit and a third visit, almost 1 year later. We evaluated mean deviation (MD), GCC and RNFL at presentation and the second visit and compared it to the mean deviation (MD) on fields at the third visit. As early as the second visit, GCC loss correlated with visual field results seen at the third visit.

摘要

可靠的视野测试是识别特发性颅内高压(IIH)患者未来视力丧失的金标准。然而,当视野测试结果不可靠时,黄斑神经节细胞复合体(GCC)分析可能会有所帮助。我们对IIH患者进行了三次就诊评估:初次就诊、随访就诊以及近1年后的第三次就诊。我们在初次就诊和第二次就诊时评估了平均偏差(MD)、GCC和视网膜神经纤维层(RNFL),并将其与第三次就诊时视野的平均偏差(MD)进行比较。早在第二次就诊时,GCC损失就与第三次就诊时的视野结果相关。

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