Department of Medicine, University of Alberta, Edmonton, AB, Canada.
Department of Medicine, Division of Rheumatology, University of Alberta, 8-130 Clinical Sciences Building, 11350 83rd Avenue NW, Edmonton, AB, T6G 2G3, Canada.
Arch Osteoporos. 2019 Feb 5;14(1):16. doi: 10.1007/s11657-019-0570-9.
Glucocorticoid-induced osteoporosis (GIOP) is common in patients prescribed with long-term glucocorticoids. Guidelines suggest patients receiving moderate-dose glucocorticoid therapy receive GIOP preventive care. Previous studies have shown preventive care rates are not optimal. We look at GIOP preventive care rates in rheumatology patients and predictors of various components of care.
Glucocorticoid-induced osteoporosis (GIOP) is a common concern in patients prescribed with long-term glucocorticoids. Studies have shown GIOP preventive care is not provided optimally in the general population; however, little is published on GIOP preventive care among patients with rheumatic disease. The objective of this study is to determine the proportion of rheumatology patients who received GIOP preventive care.
A population-based retrospective quality assurance study of adults seen at the University of Alberta Rheumatology Clinic was performed using the electronic outpatient medical record. Records of adult patients prescribed with prednisone from January 1st to December 31st, 2016 by a rheumatologist were initially included for review. Those who had been prescribed ≥ 7.5 mg/day for ≥ 3 months were assessed for concurrent GIOP preventive care.
A total of 745 discreet courses of prednisone were prescribed in 433 patients with 113 meeting the above inclusion criteria. Following the prednisone prescription, 79% were taking vitamin D, 86% were taking calcium, and 50% were prescribed with osteoporosis pharmacotherapy. Twenty-five percent of patients had DXA imaging ordered by the rheumatologist within the first 6 months; of these, 86% of patients completed the DXA.
Overall, our study shows that patients under the care of rheumatologists receive better GIOP preventative care than previously reported care in the general population. However, there is still room for improvement. In particular, men, younger patients, and rural patients seem to be at the most at risk of not receiving optimal GIOP prevention.
糖皮质激素诱导性骨质疏松症(GIOP)在长期接受糖皮质激素治疗的患者中很常见。研究表明,GIOP 的预防保健在普通人群中并未得到最佳提供;然而,在风湿性疾病患者中,关于 GIOP 预防保健的研究发表甚少。本研究旨在确定接受 GIOP 预防保健的风湿科患者的比例。
采用电子门诊病历对阿尔伯塔大学风湿病诊所的成年患者进行了基于人群的回顾性质量保证研究。最初纳入了 2016 年 1 月 1 日至 12 月 31 日期间由风湿病医生开具泼尼松处方的成年患者记录进行审查。对已开具泼尼松≥7.5mg/天且≥3 个月的患者进行了同时接受 GIOP 预防保健的评估。
在 433 名患者中,共开具了 745 个离散疗程的泼尼松处方,其中 113 名符合上述纳入标准。在开具泼尼松处方后,79%的患者服用维生素 D,86%的患者服用钙,50%的患者开具了骨质疏松症药物治疗。25%的患者在 6 个月内由风湿病医生安排了 DXA 成像;其中,86%的患者完成了 DXA。
总体而言,我们的研究表明,在接受风湿病医生治疗的患者中,GIOP 预防保健的接受程度优于先前在普通人群中报道的保健程度。然而,仍有改进的空间。特别是男性、年轻患者和农村患者似乎最有可能未接受最佳的 GIOP 预防。