Department of Nephrology, Sunshine Coast University Hospital, Birtinya, Queensland, Australia.
The University of Queensland, Sunshine Coast Clinical School, Birtinya, Queensland, Australia.
Nephrology (Carlton). 2019 Oct;24(10):1056-1063. doi: 10.1111/nep.13530. Epub 2019 Apr 29.
To compare quality of life (QOL) of caregivers of dialysis patients with the cared for patients and population norms.
The ACTIVE Dialysis study randomized participants to extended (median 24 h/week) or standard (median 12 h/week) haemodialysis hours for 12 months. A subgroup of participants and their nominated caregivers completed QOL questionnaires including the EuroQOL-5 Dimension-3 Level (EQ5D-3 L), short form-36 (SF-36, also allowing estimation of the SF-6D), as well as a bespoke questionnaire and the personal wellbeing index (PWI). Caregiver QOL was compared with dialysis patient QOL and predictors of caregiver QOL were determined using multivariable regression.
There were 54 patients and caregiver pairs, predominantly from China. Caregivers mean (SD) age was 53.4 (11.3) years, 60% were female, 71% cared for their spouse/partner, and 36% were educated to university level. Caregivers had better physical but similar mental QOL compared with dialysis patients (mean SF-36 physical component summary: 46.9 ± 8.7 vs 40.4 ± 10.2, P < 0.001; mental component summary: 47.8 ± 9.7 vs 49.6 ± 12.0, P = 0.84). Health utility measured with EQ5D-3 L was not significantly different between caregivers and dialysis patients (mean 0.869 ± 0.185 vs 0.798 ± 0.227, P = 0.083). Caregiver PWI was 43.7 ± 15.5, significantly lower than the Chinese population norm (68.2 ± 14.2, P < 0.001). Higher physical and mental QOL among caregivers was predicted by university education but not age, gender or daily hours caring.
Caregivers have higher physical and equivalent mental QOL to dialysis patients but poorer personal well-being than the Chinese population. University education predicts better QOL and may be a surrogate for socioeconomic or other factors. (NCT00649298).
比较透析患者照顾者的生活质量（QOL）与被照顾患者和人群正常值。
ACTIVE Dialysis 研究将参与者随机分配到延长（中位 24 小时/周）或标准（中位 12 小时/周）血液透析时间 12 个月。参与者的一个亚组及其指定的照顾者完成了 QOL 问卷，包括欧洲五维健康量表 3 级简表（EQ5D-3L）、36 项简短健康调查（SF-36，也允许估计 SF-6D），以及专门的问卷和个人幸福感指数（PWI）。使用多变量回归确定照顾者 QOL 与透析患者 QOL 的比较和照顾者 QOL 的预测因素。
共有 54 名患者和照顾者对，主要来自中国。照顾者的平均（SD）年龄为 53.4（11.3）岁，60%为女性，71%照顾配偶/伴侣，36%受过大学教育。与透析患者相比，照顾者的身体 QOL 更好，但心理健康状况相似（SF-36 身体成分综合评分：46.9±8.7 与 40.4±10.2，P<0.001；心理成分综合评分：47.8±9.7 与 49.6±12.0，P=0.84）。EQ5D-3L 测量的健康效用在照顾者和透析患者之间没有显著差异（平均 0.869±0.185 与 0.798±0.227，P=0.083）。照顾者的 PWI 为 43.7±15.5，明显低于中国人群正常值（68.2±14.2，P<0.001）。照顾者较高的身体和心理健康状况预测因素是大学教育，但不是年龄、性别或每天照顾的时间。
与透析患者相比，照顾者的身体 QOL 较高，心理 QOL 相等，但个人幸福感较差。大学教育预示着更好的 QOL，可能是社会经济或其他因素的替代指标。（NCT00649298）。
