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激素对干燥综合征的影响。

Influence of Hormones on Sjögren's Syndrome.

机构信息

Department of Prosthodontics, Dental Hospital, Jilin University, Changchun, Jilin 130021, China.

King Fahd Medical Research Center, King Abdulaziz University, P. O. Box 80216, Jeddah 21589, Saudi Arabia.

出版信息

Curr Pharm Des. 2018;24(35):4167-4176. doi: 10.2174/1381612824666181010153536.

DOI:10.2174/1381612824666181010153536
PMID:30724137
Abstract

Sjögren's syndrome (SS) is an immune system oral disorder that is characterized generally by dry mouth and eyes. In this review, SS classification, presentation and pathogenesis are briefly discussed. Moreover, the epidemiology of SS regarding sex, age and association with other complications are also presented. This review also addresses the interactions between endocrine axes and SS, and the important findings up to regarding hormone treatment of this syndrome. The main hormones discussed in this review includes Adrenocorticotropic hormone (ACTH), Follicle-stimulating hormone (FSH), Luteinizing hormone (LH), Thyroid-stimulating hormone (TSH), and prolactin.

摘要

干燥综合征(SS)是一种免疫系统口腔疾病,一般表现为口干和眼干。本文简要讨论了 SS 的分类、表现和发病机制。此外,还介绍了 SS 与性别、年龄和其他并发症的关联的流行病学。本文还探讨了内分泌轴与 SS 之间的相互作用,以及关于该综合征激素治疗的重要发现。本文讨论的主要激素包括促肾上腺皮质激素(ACTH)、卵泡刺激素(FSH)、黄体生成素(LH)、促甲状腺激素(TSH)和催乳素。

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1
Influence of Hormones on Sjögren's Syndrome.激素对干燥综合征的影响。
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2
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MedComm (2020). 2025 Jul 11;6(7):e70297. doi: 10.1002/mco2.70297. eCollection 2025 Jul.
2
A comprehensive review of Sjögren's syndrome: Classification criteria, risk factors, and signaling pathways.干燥综合征综合综述:分类标准、危险因素及信号通路
Heliyon. 2024 Aug 15;10(17):e36220. doi: 10.1016/j.heliyon.2024.e36220. eCollection 2024 Sep 15.
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Infection as an Early Sign of Subsequent Sjögren's Syndrome: A Population-Based Matched Cohort Study.
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Prolactin Increases the Frequency of Follicular T Helper Cells with Enhanced IL21 Secretion and OX40 Expression in Lupus-Prone MRL/lpr Mice.催乳素增加狼疮易感 MRL/lpr 小鼠滤泡辅助性 T 细胞的频率,增强其 IL21 分泌和 OX40 表达。
J Immunol Res. 2021 Mar 8;2021:6630715. doi: 10.1155/2021/6630715. eCollection 2021.
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J Clin Med. 2020 Jul 20;9(7):2299. doi: 10.3390/jcm9072299.