Department of Biotechnology, University of Calicut, Malappuram, Kerala, India.
School of Health Sciences, University of Calicut, Malappuram, Kerala, India.
Nat Prod Res. 2020 Aug;34(16):2336-2340. doi: 10.1080/14786419.2018.1533826. Epub 2019 Feb 6.
Hydro-distilled essential oils, from fresh rhizomes and leaves of Škorničk., M.Sabu & Prasanthk., characterized by GC-MS revealed the presence of thirty three and twenty three compounds therein respectively. Whilst estrone methyl ether (3-Methoxyestra-1,3,5(10)-trien-17-one) was the major component in rhizome oil (47.35%), sesquiterpene hydrocarbons predominated as the major group (63.92%) in leaf oil with a higher preponderance of β-caryophyllene (25.48%), β-farnesene (19.47%) and α-humulene (11.01%). Weak antioxidant activities observed in these oils determined by DPPH and ABTS methods were apparently influenced both by the oil composition and the assay conditions. Rhizome oil showed higher antiproliferative activity than leaf oil against leukemic K562 (IC-6.8µg/mL) and colorectal HCT116 (IC-8.5µg/mL) cancer cell lines. This first report reveals composition and biological activities of essential oils from .
水蒸馏的精油，来自新鲜的 Škorničk.、M.Sabu 和 Prasanthk. 的根茎和叶子，通过 GC-MS 分析表明，分别存在三十三种和二十三种化合物。在根茎油中，雌酮甲醚（3-甲氧基雌-1,3,5(10)-三烯-17-酮）是主要成分（47.35%），而倍半萜烃则是叶子油中的主要成分（63.92%），β-石竹烯（25.48%）、β-法呢烯（19.47%）和α-葎草烯（11.01%）的含量较高。通过 DPPH 和 ABTS 方法测定，这些油表现出较弱的抗氧化活性，显然受到油的组成和测定条件的影响。根茎油对白血病 K562（IC-6.8μg/mL）和结直肠 HCT116（IC-8.5μg/mL）癌细胞系的增殖活性高于叶子油。这是首次报道来自 Škorničk.的精油的组成和生物活性。
