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射频子宫内膜消融术治疗慢性肾衰竭妇女月经过多。

Radiofrequency endometrial ablation for treating heavy menstrual bleeding in women with chronic renal failure.

机构信息

a Department of Obstetrics and Gynecology , The Third Xiangya Hospital of Central South University , Changsha , China.

出版信息

Int J Hyperthermia. 2018;35(1):612-616. doi: 10.1080/02656736.2018.1515445. Epub 2018 Nov 1.

Abstract

OBJECTIVE

The study objective was to retrospectively evaluate the efficacy and safety of radiofrequency endometrial ablation in treating heavy menstrual bleeding (HMB) in women with chronic renal failure (CRF).

METHOD

Fifty-eight patients with CRF undergoing radiofrequency endometrial ablation in our hospital between January 2013 and July 2017 and for whom complete follow-up data were available were included. Outcome measures included amenorrhea, treatment failure and operative complications.

RESULTS

The mean patient age was 41.4 ± 7.7 years, the mean preoperative hemoglobin level was 69.6 ± 19.3 g/dL, the mean preoperative serum creatinine level was 879.1 ± 415.4 µmol/L, and the mean urea level was 18.2 ± 7.1 mmol/L. The mean treatment time for radiofrequency endometrial ablation was 61.7 ± 18.8 s. The median volume of estimated blood loss during the procedure was 10 mL (a range of 2-50 mL). On average, the study subjects were monitored for 24.4 months (a range of 6-60 months). The average amenorrhea rate was 89.7%. Only 2 (3.4%) patients required additional gynecologic surgery after endometrial ablation. Intra- and postoperative complications were not observed.

CONCLUSION

Radiofrequency endometrial ablation was demonstrated to be safe and effective for the treatment of HMB in women with CRF.

摘要

目的

本研究旨在回顾性评估射频子宫内膜消融术治疗慢性肾衰竭(CRF)女性月经过多(HMB)的疗效和安全性。

方法

选取 2013 年 1 月至 2017 年 7 月在我院行射频子宫内膜消融术的 58 例 CRF 患者,所有患者均获得完整随访资料。观察指标包括闭经、治疗失败和手术并发症。

结果

患者年龄(41.4±7.7)岁,术前血红蛋白水平(69.6±19.3)g/dL,术前血清肌酐水平(879.1±415.4)µmol/L,术前尿素水平(18.2±7.1)mmol/L。射频子宫内膜消融术的平均治疗时间为(61.7±18.8)s。术中估计出血量中位数为 10 mL(范围为 2-50 mL)。平均随访(24.4±6.0)个月(范围为 6-60 个月)。闭经率平均为 89.7%。仅 2 例(3.4%)患者在子宫内膜消融后需要进一步行妇科手术。术中及术后无并发症发生。

结论

射频子宫内膜消融术治疗 CRF 女性 HMB 安全有效。

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